Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Life Histories

Life Histories

Life Tables

Life Tables

A life table is a statistical tool that summarizes the mortality and survival patterns of a population, providing detailed insights into the likelihood of survival or death across different age intervals within a cohort. By organizing data on survival probabilities and mortality rates, life tables offer a clear snapshot of population dynamics over time. They are extensively used in demography, public health, actuarial science, and ecology to analyze life expectancy, design health interventions,...

Applications of Life Tables

Applications of Life Tables

Life tables are versatile across various fields, providing a quantitative basis for analyzing mortality and survival rates. Whether used by demographers, actuaries, epidemiologists, or sociologists, life tables offer valuable insights into the dynamics of life and death, facilitating informed decisions in public health, insurance, conservation, and beyond. Their broad applicability highlights the interconnectedness of demographic data with practical outcomes in everyday life and strategic...

Three Developmental Domains

Three Developmental Domains

Human development is typically examined across three main domains: physical, cognitive, and socio-emotional. These domains represent the significant areas of change and continuity throughout the lifespan, from infancy to late adulthood.
Physical Development
Physical processes, also known as maturation, encompass the biological changes that occur across an individual's life. These changes begin with genetic inheritance and continue through various stages, including growth in height and weight,...

Introduction to Developmental Psychology

Introduction to Developmental Psychology

Developmental psychology explores the changes and continuities in human abilities throughout life, encompassing physical, cognitive, linguistic, and social dimensions. Human development is not restricted to growth, but includes aspects of decline, particularly in physical abilities as individuals age. Developmental psychologists seek to understand how people change as they age and how their mental and social skills evolve.Developmental MilestonesA key concept in developmental psychology is...

Cognitive Development During Adulthood

Cognitive Development During Adulthood

Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Evaluating the Utility of Staphylococcus aureus Nasal Screening in Preventing Surgical Site Infections in Elective Orthopaedic Surgery: A Propensity-Matched Analysis.

The Journal of bone and joint surgery. American volume·2026

Same author

Comparing Brain-Behavior Relationships Across Dimensional, Tail-Sampled, and Propensity-Matched Models.

bioRxiv : the preprint server for biology·2025

Same author

Environmental variables influence the relationship between maternal depressive symptoms and toddlers' neurocognitive and affective outcomes.

Journal of affective disorders·2024

Same author

Molecular signatures of cortical expansion in the human foetal brain.

Nature communications·2024

Same author

UNITY: A low-field magnetic resonance neuroimaging initiative to characterize neurodevelopment in low and middle-income settings.

Developmental cognitive neuroscience·2024

Same author

Molecular signatures of cortical expansion in the human fetal brain.

bioRxiv : the preprint server for biology·2024

Search research articles

Related Experiment Video

Updated: Sep 27, 2025

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine

Published on: January 26, 2024

Brain charts for the human lifespan.

R A I Bethlehem^1,2, J Seidlitz^3,4,5, S R White^6,7

¹Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, UK. rb643@medschl.cam.ac.uk.

|April 7, 2022

Summary

This summary is machine-generated.

Brain charts provide reference standards for brain morphology using MRI data from over 100,000 individuals. These charts enable quantification of brain development and individual differences across the lifespan.

More Related Videos

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Published on: December 18, 2016

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach

Published on: February 14, 2014

Related Experiment Videos

Last Updated: Sep 27, 2025

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine

Author Spotlight: Automated Lifespan Monitoring – Discovering Aging Dynamics with the Lifespan Machine

Published on: January 26, 2024

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Published on: December 18, 2016

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach

Published on: February 14, 2014

Area of Science:

Neuroimaging
Developmental Neuroscience
Biostatistics

Background:

Neuroimaging is widely used in brain research, but lacks standardized reference charts for individual brain metrics over time.
Existing anthropometric growth charts provide benchmarks for physical development, highlighting a need for similar tools in neuroscience.

Purpose of the Study:

To create an interactive, open-access resource (brainchart.io) for benchmarking brain morphology from MRI data.
To establish reference standards for brain structure quantification across the human lifespan.

Main Methods:

Aggregated 123,984 MRI scans from 101,457 participants (fetal to 100 years old) across over 100 studies.
Quantified MRI metrics using centile scores relative to lifespan trajectories of brain structural changes.
Assessed stability, robustness to technical variations, and heritability of centile scores.

Main Results:

Identified novel neurodevelopmental milestones and demonstrated high individual stability in brain structure over time.
Brain charts showed robustness to inter-study methodological differences.
Centile scores revealed increased heritability and provided a standardized measure for neuroanatomical variation in disorders.

Conclusions:

Brain charts offer a crucial tool for robustly quantifying individual variation in neuroimaging phenotypes against normative trajectories.
This resource facilitates standardized comparison of brain structure across development and in clinical populations.