A Study on Risk Factors Associated with Reflux Esophagitis in Patients Undergoing Esophageal Cancer Surgery

Area of Science:

• Gastroenterology
• Surgical Oncology
• Clinical Research

Background:

• Reflux esophagitis is a common complication following esophageal cancer surgery.
• Identifying risk factors is crucial for effective prevention and management.

Purpose of the Study:

• To investigate the risk factors associated with reflux esophagitis in patients who have undergone esophageal cancer surgery.
• To provide a basis for the prevention and treatment of post-operative reflux esophagitis.

Main Methods:

• A retrospective study of 300 patients with esophageal cancer who underwent surgery between January 2018 and December 2020.
• Patients were divided into groups based on the occurrence (n=45) or non-occurrence (n=255) of reflux esophagitis post-surgery.
• Statistical analysis, including logistic regression, was used to identify significant risk factors.

Main Results:

• Significant differences were observed in body weight, BMI, resected esophagus length, surgical approach, intraoperative blood loss, gastrointestinal decompression volume, and surgery time.
• Logistic multivariate analysis identified resected esophagus length, whole stomach reconstruction, intraoperative blood loss, and surgery time as significant risk factors for reflux esophagitis.

Conclusions:

• Resected esophagus length, whole stomach reconstruction, intraoperative blood loss, and surgery time are identified risk factors for reflux esophagitis after esophageal cancer surgery.
• Clinical practice should involve selecting appropriate surgical approaches and strengthening preventative measures for reflux esophagitis.