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Updated: Sep 27, 2025

Combining QD-FRET and Microfluidics to Monitor DNA Nanocomplex Self-Assembly in Real-Time
Published on: August 26, 2009
Tuning the binding configurations of single-molecule junctions by molecular co-assembly
Ling Tong1, Shu-Yi Bao1, Chen-Chen Jiang1
1Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, Institute of Physical Chemistry, Zhejiang Normal University, Jinhua 321004, China. yahaowang@zjnu.edu.cn.
Abstract:
Significant variability issues in metal-molecule contacts, such as adsorption geometry, lead to characteristic variability in the electrical responses of individual molecules. Herein, co-assembling 1-ethylimidazole (EIM) on Au(111) has been shown to be a feasible and effective strategy for tuning the binding configurations of pyridine-linked molecular junctions in the most common aqueous environments and atmospheric environments. The single-molecule conductance measurements clearly show a transition from multiple conductance peaks to a single conductance peak with increasing EIM concentration. Raman spectroscopy and DFT calculations suggest that the thermodynamically favorable EIM adsorbate results in the vertical orientation of the bipyridine.
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