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[Diagnostic approach to chronic kidney disease]
P Delanaye1,2, B Dubois1, E Cavalier3
1Service de Néphrologie, Dialyse et Transplantation, CHU Liège, Belgique.
Revue Medicale De Liege
|April 7, 2022
Summary
Chronic kidney disease (CKD) impacts 7% of people, often presenting with vague symptoms. Early CKD diagnosis relies on identifying renal abnormalities, proteinuria, or reduced glomerular filtration rate (GFR) persisting over three months.
Area of Science:
- Nephrology
- Internal Medicine
- Public Health
Background:
- Chronic kidney disease (CKD) affects approximately 7% of the global population, contributing significantly to morbidity and mortality, particularly cardiovascular disease.
- Advanced CKD necessitates intensive and expensive treatments like dialysis or kidney transplantation, posing a burden on patients and healthcare systems.
- CKD often presents with subtle, non-specific symptoms, hindering early detection and timely management.
Framework:
- Diagnostic criteria for CKD involve renal morphological abnormalities, proteinuria exceeding 150 mg/g creatinine, or a glomerular filtration rate (GFR) below 60 ml/min/1.73 m².
- Chronicity of renal damage is established when these abnormalities persist for longer than three months.
- This framework guides the systematic evaluation of suspected CKD cases.
Implementation:
- Utilizing an exemplary clinical case to illustrate the diagnostic pathway for suspected CKD.
- Detailed explanation of the step-by-step diagnostic process.
- Emphasis on integrating clinical findings with laboratory and imaging data.
Implications:
- Improved early identification of CKD patients, enabling prompt intervention.
- Potential reduction in CKD-related complications and healthcare costs.
- Enhanced understanding of CKD diagnostic criteria for clinicians and healthcare providers.
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