Copper-Catalyzed Highly Selective Hydrosilylation of Silyl or Boryl Alkene: A Method for Preparing Chiral Geminated Disilyl and Borylsilyl Reagents
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Updated: Sep 27, 2025

Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides
Published on: May 26, 2019
Min Zhang1, Yuqi Ji1, Zheng Zhang1
1Institute of Molecular Plus, Tianjin Key Laboratory of Molecular Optoelectronic Science, School of Chemical Engineering and Technology, Tianjin University, Weijin Road 92, Tianjin 300072, China.
Abstract:
The copper-catalyzed highly selective hydrosilylation of silyl or boryl alkene has been developed. This chemistry could afford a practical method for preparing chiral geminated disilyl and borylsilyl reagents, which are useful organosilanes and versatile synthons for organic synthesis. The experimental data suggested that this reaction could be compatible with a variety of functional groups. Furthermore, the utility of the gem-dimetal compounds, which could be prepared by this chemistry, has been well illustrated by further transformations.
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