Promoting a gender-affirming environment in research: implications for research nurses

Area of Science:

• Health Equity
• Clinical Research
• Transgender Health

Background:

• Growing transgender population globally faces significant healthcare disparities.
• Mistrust of the medical community and fear of stigmatization deter transgender individuals from sharing personal health information.
• Inequities extend to clinical research, impacting participation and trust.

Purpose of the Study:

• To explore barriers to transgender participation in clinical research.
• To examine the role of clinical research staff, particularly nurses, in improving engagement.
• To initiate a dialogue on inclusive research practices.

Main Methods:

• Literature review and expert discussion on barriers and facilitators.
• Analysis of safety, data integrity, and data management considerations.
• Development of recommendations for research staff training.

Main Results:

• Identified significant barriers including stigma, mistrust, and lack of knowledgeable research staff.
• Highlighted the critical role of clinical research nurses in fostering trust and engagement.
• Emphasized the need for education on gender-affirming care for research professionals.

Conclusions:

• Addressing disparities requires fostering a competent and gender-affirming research environment.
• Clinical research nurses are pivotal in promoting transgender inclusion.
• Improved training and practices are essential for equitable clinical research participation.