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Updated: Sep 27, 2025

Experimental Human Pneumococcal Carriage
Published on: February 15, 2013
Pneumococcus beyond an Austrian syndrome - A case report.
Gonçalo Guerreiro1, André Pina Monteiro2, Luís Coelho1
1Unidade de Cuidados Intensivos Polivalente, Hospital de São Francisco Xavier, Centro Hospitalar Lisboa Ocidental, Lisbon, Portugal.
Austrian syndrome, a rare triad of endocarditis, pneumonia, and meningitis caused by Streptococcus pneumoniae, presents a high mortality risk. This case highlights an unusual presentation in an elderly, splenectomized patient with septic arthritis.
Area of Science:
- Infectious Diseases
- Cardiology
- Neurology
Background:
- Austrian syndrome is a rare, severe condition defined by endocarditis, pneumonia, and meningitis, typically caused by Streptococcus pneumoniae.
- The syndrome is associated with significant morbidity and mortality, primarily due to cardiac valve destruction.
Observation:
- A case report details an elderly patient who underwent splenectomy.
- This patient presented with an atypical form of Austrian syndrome, including septic arthritis complicated by endocarditis, septic cerebral emboli, meningitis, and pneumonia.
Findings:
- The patient's presentation was unusual, involving septic arthritis as a primary complication.
- Despite receiving appropriate medical treatment, the patient's condition deteriorated rapidly.
Implications:
- This case underscores the aggressive nature of Austrian syndrome and its potential for varied clinical manifestations.
- It emphasizes the poor prognosis associated with this condition, particularly in asplenic elderly individuals.
- The report highlights the importance of considering Austrian syndrome in patients with complex infectious presentations, even with atypical initial symptoms.
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