Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Introduction to Fibroblasts01:09

Introduction to Fibroblasts

3.2K
Rudolph Virchow discovered spindle-shaped cells called fibroblasts in 1858. Inactive fibroblasts, called fibrocytes, become activated by various stimuli, such as growth factors and inflammatory cytokines. Activated fibroblasts play a crucial role in wound healing, inflammation, formation of new blood vessels, and cancer progression. Uncontrolled activation of fibroblasts results in fibrosis, the excess deposition of fibrous tissue, which can lead to scarring and affect normal organs. This...
3.2K
Association Areas of the Cortex01:21

Association Areas of the Cortex

6.5K
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
6.5K
Clot Retraction and Fibrinolysis01:16

Clot Retraction and Fibrinolysis

7.0K
After a fibrin clot is formed, the next step is clot retraction, a vital process facilitated by platelet contractile proteins, such as actin and myosin. These proteins pull the fibrin strands closer together and condense the clot. This action reduces the size of the clot, creating a smaller, denser structure that effectively seals off the damaged vessel. Clot retraction consolidates the clot and helps with wound healing by bringing the edges of the damaged blood vessel closer together.
7.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Disseminated telangiectasias in a patient with breast cancer.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2026
Same author

The follicular microbiome in hair-follicle-associated inflammatory diseases: A systematic review.

Clinical and experimental dermatology·2026
Same author

Hair Loss in Patients on Glucagon-Like Peptide 1 Receptor Agonists: Understanding Risks and Managing Outcomes.

Dermatology and therapy·2026
Same author

Skin and Wound Infection Models to Test Host-Pathogen Interactions and Evaluate Topical Antimicrobial Treatments.

Methods in molecular biology (Clifton, N.J.)·2026
Same author

S3 guideline diagnostics and therapy in alopecia areata - Part 2: Therapy, psychosocial and cosmetic support.

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2026
Same author

Genome-wide association study of atopic and autoimmune comorbidities in alopecia areata.

Frontiers in immunology·2026

Related Experiment Video

Updated: Sep 27, 2025

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia
03:22

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia

Published on: January 27, 2018

15.2K

[Frontal fibrosing alopecia-update].

Ulrike Blume-Peytavi1, Kathrin Hillmann2, Andria Constantinou2

  • 1Klinik für Dermatologie, Venerologie und Allergologie, Clinical Research Center for Hair and Skin Science, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117, Berlin, Deutschland. ulrike.blume-peytavi@charite.de.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|April 8, 2022
PubMed
Summary

Frontal fibrosing alopecia (FFA) is an increasing condition affecting diverse demographics. Early recognition and understanding of its varied presentation are crucial for effective patient management and treatment strategies.

Keywords:
Anti-inflammatory treatmentHair follicle lossLichen planopilarisLymphocytic inflammationScarring alopecia

More Related Videos

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
06:41

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis

Published on: March 9, 2015

9.1K
Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

28.6K

Related Experiment Videos

Last Updated: Sep 27, 2025

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia
03:22

Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia

Published on: January 27, 2018

15.2K
A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
06:41

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis

Published on: March 9, 2015

9.1K
Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

28.6K

Area of Science:

  • Dermatology
  • Trichology

Background:

  • Frontal fibrosing alopecia (FFA) is increasingly diagnosed in clinical settings.
  • Recognition of its distinct clinical features and symptoms is vital for patient care.

Purpose of the Study:

  • To provide insights into the pathogenesis, triggers, clinical course, and treatment of FFA.
  • To highlight the expanding clinical spectrum of FFA beyond typical presentations.

Main Methods:

  • Review of experimental studies and case series on FFA.
  • Analysis of clinical presentations and disease progression.

Main Results:

  • FFA affects a broader demographic, including younger women, men, and adolescents.
  • Clinical manifestations include eyebrow and body hair loss, and facial papules.
  • Pathogenesis involves inflammation and fibrosis, leading to permanent hair follicle loss, similar to lichen planopilaris.

Conclusions:

  • Current FFA management focuses on anti-inflammatory therapies.
  • The chronic, progressive nature of FFA, even with minimal inflammation, presents therapeutic challenges.
  • Further controlled studies are needed for evidence-based recommendations and novel treatments.