[Chronic cerebral ischemia and dizziness]

Area of Science:

• Neurology
• Geriatrics
• Otolaryngology

Background:

• Dizziness and vertigo are highly prevalent in older adults, encompassing central and peripheral vestibular disorders, instability, and balance issues.
• While chronic cerebral ischemia is often suspected as a cause of dizziness in the elderly, its role is frequently overestimated, and mechanisms remain unclear.
• A significant portion of dizziness in older individuals remains "unexplained" even after thorough vestibular assessment.

Purpose of the Study:

• To investigate the relationship between "unexplained" dizziness and chronic cerebrovascular pathology in the elderly.
• To explore proposed theories explaining the mechanisms linking these conditions.
• To evaluate the therapeutic role and mechanisms of choline alphoscerate in treating dizziness associated with chronic cerebral ischemia.

Main Methods:

• Review of recent studies examining the association between "unexplained" dizziness and chronic cerebrovascular pathology.
• Analysis of proposed etiological mechanisms for this association.
• Assessment of clinical evidence supporting the use of choline alphoscerate in managing dizziness in patients with chronic cerebral ischemia.

Main Results:

• Recent studies indicate a demonstrable relationship between "unexplained" dizziness and chronic cerebrovascular pathology.
• Several theories are proposed to elucidate the mechanisms underlying this association.
• The efficacy of choline alphoscerate in managing dizziness in the context of chronic cerebral ischemia has been demonstrated.

Conclusions:

• "Unexplained" dizziness in the elderly may be linked to underlying chronic cerebrovascular issues.
• Further research into the proposed mechanisms is warranted.
• Choline alphoscerate shows promise as a therapeutic agent for dizziness in patients with chronic cerebral ischemia, with its positive effects and usage prospects meriting further investigation.