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Case Report: A Rare Fungal Keratitis Caused by Plectosphaerella Cucumerina
Zhongcheng Shen1,2, Yawei Zhang3, Fangting Li1,2
1Department of Ophthalmology, People's Hospital, Peking University, Beijing, China.
Purpose:
To report a rare case of fungal keratitis caused by Plectosphaerella cucumerina.
Methods:
This study retrospectively reviewed the medical records of a case of fungal keratitis.
Results:
Silt-lamp biomicroscopy revealed corneal infiltration and epithelial defects. Anterior segment optical coherence tomography (AS-OCT) and in vivo confocal microscopy (IVCM) were performed to assist in the diagnosis and evaluate corneal conditions. The isolate was identified as Plectosphaerella cucumerina by MALDI-TOF mass spectrometry. The patient was treated with topical 5% pimaricin and oral voriconazole for 1 month and recovered.
Conclusion:
Fungal keratitis caused by Plectosphaerella cucumerina is rare. AS-OCT and IVCM can help locate the lesion and diagnose fungal keratitis. Furthermore, MALDI-TOF mass spectrometry showed potential prospects in the identification of filamentous fungi. Plectosphaerella cucumerina rarely infects humans and is sensitive to antifungal agents such as pimaricin and voriconazole.
