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Updated: Sep 27, 2025

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
Seasonal changes in mood and behavior contribute to suicidality and worthlessness in a population-based study
Raimo Palmu1, Seppo Koskinen2, Timo Partonen2
1Department of Psychiatry, University of Helsinki and Helsinki University Hospital, P.O. Box 590 (Välskärinkatu 12), FI-00029, HUS, Finland; Department of Public Health and Welfare, Finnish Institute for Health and Welfare, P.O. Box 30 (Mannerheimintie 166), FI-00271, Helsinki, Finland.
Abstract:
Limited evidence suggests that the seasonal changes in mood and behavior may associate with suicidality and the feelings of worthlessness, but these associations have not been analyzed in large population-based data. A random sample of adults (n = 4069), representative of the general population living in Finland, attended a nationwide health examination survey. Seasonal variations (seasonality) in mood and behavior were analyzed with the six items of global seasonality score (GSS) and the experienced problem due to these variations. Their impact on suicidality as well as on the feelings of worthlessness were analyzed using logistic regression models. After adjusting for age and gender, the GSS, each of its six items and the experienced problem due to the seasonal variations in mood and behavior all showed separately a significant association with suicidality as well as with worthlessness. After further adjustment for the education level and region of residence, the GSS, its mood item and the experienced problem remained significantly associated with both suicidality and worthlessness. Seasonal variations in mood and behavior have a significant association with both suicidality and worthlessness.
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