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Analysis on short-term change of macular function and the correlates after intravitreal conbercept for CRVO-ME
Yun-Chang Wang1, Rong-Rong Li2, Yi Cai2
1The Key Laboratory of Ocular of Heibei Province, The Treatment Centre of Ocular Disease of Hebei Province, Heibei Eye Hospital, Number 399 quan bei dong da jie, Xingtai, 054001, Hebei Province, China. wycocular@163.com.
Aim:
To study the short-term change of macular function and the correlates after intravitreal conbercept for CRVO-ME.
Study Design:
Prospective, clinical study.
Methods:
Twenty Three patients(23 eyes) were recruited, who were non-ischemia central retinal vein occlusion diagnosed by FFA (fundus fluorescein angiography) and treated with intravitreal conbercept for macular edema, best - corrected visual acuity ( BCVA), central macular thickness(CMT), amplitude density of P1 wave and implicit time of P1,N1 wave from ring 1 and ring 2 of mf-ERG were measured before and 1 week、2 month after treatment.
Results:
Compared to the baseline, BCVA、CMT、amplitude density of P1 wave and implicit time of P1,N1 wave from ring 1 and ring 2 were greatly improved at 1 W、2 M after treatment; better results were gained at 2 M compared to 1 W; Pearson correlation analysis shows no significantly correlation between the improvement of mf-ERG with the change of BCVA、CMT.
Conclusion:
The BCVA、the structure and the function of macular were greatly improved after intravitreal conbercept for central retinal vein occlusion induced macular edema; however no significantly correlation between the improvement of the function of macular with the strcture of macular and BCVA.
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