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Updated: Sep 27, 2025

Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
Published on: September 26, 2018
Long-term cardiovascular risk prediction in the emergency department: a mixed-methods study protocol
Charles Reynard1,2, Brian McMillan3, Anisa Jafar4
1Division of Cardiovascular Sciences, The University of Manchester, Manchester, UK charlie.reynard@manchester.ac.uk.
This study investigates using emergency department data to predict long-term cardiovascular disease (CVD) outcomes. Findings will inform a new care pathway to improve patient care and reduce healthcare inefficiencies.
Area of Science:
- Cardiology
- Public Health
- Health Services Research
Background:
- Cardiovascular disease (CVD) is a leading cause of preventable death in Europe.
- Emergency departments (EDs) collect CVD risk factors but often fail to act on them.
- Utilizing routinely collected ED data could improve patient care and system efficiency.
Purpose of the Study:
- To determine the prognostic value of routinely collected ED data for long-term CVD outcomes.
- To co-design a prototype care pathway for implementing this knowledge with stakeholders.
- To enhance holistic patient care and reduce health system inefficiencies.
Main Methods:
- Mixed-methods approach combining quantitative and qualitative research.
- Quantitative analysis of ~21,000 chest pain patient episodes with 7.3-year follow-up using Cox regression.
- Qualitative semi-structured interviews and thematic analysis to co-design a care pathway prototype.
Main Results:
- Investigating the prognostic characteristics of routinely collected ED data for long-term CVD outcomes.
- Developing a logic model based on thematic analysis to structure pathway development.
- Co-designing a prototype care pathway with stakeholders for improved CVD risk management.
Conclusions:
- Routinely collected ED data holds prognostic value for long-term CVD outcomes.
- A co-designed care pathway can effectively integrate this knowledge into clinical practice.
- This approach promises more efficient and holistic cardiovascular care.
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