Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effect of bite planes on deepbite correction with clear aligners.

Clinical oral investigations·2026
Same author

Minimal Peptide Surfactants for Long-Lasting Nanoemulsions via Noncovalent Interfacial Interactions.

ACS applied materials & interfaces·2026
Same author

Dual-stiffness nanoparticles for compartment-specific drug delivery in stroke.

Nature communications·2026
Same author

Correction: Rapid, Scalable, and Cost-Effective Manufacturing of Uniform Non-Enveloped, Tag-Free Virus-Like Particles.

Current protocols·2026
Same author

Topical delivery of high-drug-loading nanoparticle gels for psoriasis treatment.

Journal of nanobiotechnology·2026
Same author

Rapid, Scalable, and Cost-Effective Manufacturing of Uniform Non-Enveloped, Tag-Free Virus-Like Particles.

Current protocols·2026
Same journal

Cell Membrane-Engineered FePDA Nanoparticles Integrate Ferroptosis and Antitumor Immunity.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Finding the Perfect Match: Investigation of 1,2-Diketone-Based Materials for Use as Cathode Active Material in Rechargeable Magnesium Batteries.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Stabilization of Cu Species in UiO-66 Metal-Organic Framework for CO<sub>2</sub>-to-Methanol: Insights From Operando X-ray and Electron Microscopy Studies.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

BODIPY Photocage-Based Injectable Hydrogel for Light-Controlled Nanoparticle Release.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Multifunctional Nanodiamond Conjugate With a Tumor-Specific EGFR-Targeting Peptide and Photoactivated CO Release for Improved Therapeutic Efficacy in Head and Neck Cancers.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Multifunctional Self-Bonding Biocomposites Enabled by Uniform Dispersion of Carbon Nanotube via In Situ Lignin and Multiple Noncovalent Bonds.

Small (Weinheim an der Bergstrasse, Germany)·2026
See all related articles

Related Experiment Video

Updated: Sep 27, 2025

Computer Numerical Control Micromilling of a Microfluidic Acrylic Device with a Staggered Restriction for Magnetic Nanoparticle-Based Immunoassays
09:58

Computer Numerical Control Micromilling of a Microfluidic Acrylic Device with a Staggered Restriction for Magnetic Nanoparticle-Based Immunoassays

Published on: June 23, 2022

2.2K

Microfluidic Nanoparticles for Drug Delivery.

Yun Liu1, Guangze Yang1, Yue Hui2

  • 1Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD, 4072, Australia.

Small (Weinheim an Der Bergstrasse, Germany)
|April 9, 2022
PubMed
Summary
This summary is machine-generated.

Microfluidics technology enables precise control over nanoparticle synthesis for drug delivery. This review highlights advancements in microfluidic methods for creating organic, inorganic, and hybrid nanoparticles for pharmaceutical applications.

Keywords:
drug deliverylipidsmicrofluidicsnanomedicinenanoparticlespolymers

More Related Videos

Production of siRNA-Loaded Lipid Nanoparticles using a Microfluidic Device
06:02

Production of siRNA-Loaded Lipid Nanoparticles using a Microfluidic Device

Published on: March 22, 2022

9.5K
Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles
10:12

Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles

Published on: January 7, 2019

22.5K

Related Experiment Videos

Last Updated: Sep 27, 2025

Computer Numerical Control Micromilling of a Microfluidic Acrylic Device with a Staggered Restriction for Magnetic Nanoparticle-Based Immunoassays
09:58

Computer Numerical Control Micromilling of a Microfluidic Acrylic Device with a Staggered Restriction for Magnetic Nanoparticle-Based Immunoassays

Published on: June 23, 2022

2.2K
Production of siRNA-Loaded Lipid Nanoparticles using a Microfluidic Device
06:02

Production of siRNA-Loaded Lipid Nanoparticles using a Microfluidic Device

Published on: March 22, 2022

9.5K
Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles
10:12

Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles

Published on: January 7, 2019

22.5K

Area of Science:

  • Nanotechnology
  • Materials Science
  • Pharmaceutical Sciences

Background:

  • Nanoparticles (NPs) are crucial for drug delivery, with microfluidics offering precise control over their properties.
  • The success of mRNA vaccines manufactured using microfluidics signifies a major advancement for pharmaceutical applications.
  • Microfluidics technology is proving feasible for the industrial-scale production of nanoparticles.

Purpose of the Study:

  • To critically review recent advancements in microfluidic synthesis of nanoparticles for drug delivery.
  • To summarize microfluidic methods for producing organic nanoparticles like liposomes, lipid NPs, and polymer NPs.
  • To discuss the synthesis and applications of inorganic and hybrid nanoparticles using microfluidics.

Main Methods:

  • Review of established microfluidic techniques for nanoparticle synthesis.
  • Analysis of synthesis mechanisms for various organic nanoparticle types.
  • Discussion of microfluidic approaches for inorganic and hybrid nanoparticle fabrication.

Main Results:

  • Microfluidics enables precise control over nanoparticle characteristics, crucial for drug delivery efficacy.
  • Successful synthesis of clinically relevant organic nanoparticles (liposomes, lipid NPs, polymer NPs) via microfluidics.
  • Demonstrated microfluidic synthesis of diverse inorganic (silica, metal, quantum dots) and hybrid nanoparticles.

Conclusions:

  • Microfluidics is a powerful and scalable technology for manufacturing nanoparticles for drug delivery.
  • The precise control offered by microfluidics enhances the potential of nanoparticles in pharmaceutical applications.
  • Continued research in microfluidic NP synthesis promises expanded applications in various drug delivery strategies.