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Probiotic Formulations: A Patent Landscaping Using the Text Mining Approach.

Swayamprakash Patel1, Mruduka S Patel2, Ashish D Patel3

  • 1Ramanbhai Patel College of Pharmacy, Charotar University of Science and Technology (CHARUSAT), CHARUSAT Campus, Changa, 388421, India. Swayamprakashpatel.ph@charusat.ac.in.

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This review analyzes over 400 probiotic patents from 2000-2020, revealing diverse applications from food to medicine. It highlights current innovations and identifies unexplored areas for future probiotic product development.

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Area of Science:

  • Microbiology and Biotechnology
  • Intellectual Property Law
  • Pharmaceutical Sciences

Background:

  • The proliferation of probiotic research has led to numerous innovative products and patents.
  • Understanding patented probiotic formulations offers insights into current applications and market trends.

Purpose of the Study:

  • To conduct a comprehensive patent landscape review of probiotic-based preparations.
  • To identify technological clusters and emerging innovations in probiotic formulations.

Main Methods:

  • A patent search was conducted using commercial databases and PatSeer Pro®.
  • Text-mining analysis was applied to over 400 patents filed between 2000 and 2020.
  • Keywords "Formulation" and "Composition" yielded over 3700 initial patent results.

Main Results:

  • Nineteen distinct technological clusters were identified, encompassing applications in animal feed, human food, cosmetics, and therapeutics.
  • Key areas of innovation include probiotic products for depression, diabetes, Parkinson's disease, tumors, and acne.
  • Novel applications such as probiotic-layered condoms and products for alcoholism were also uncovered.

Conclusions:

  • The patent landscape reveals a dynamic and expanding field of probiotic-based preparations.
  • Significant opportunities exist for further innovation in unexplored areas of probiotic applications.