Arginine, administrated in various ways, as a stimulator of insulin secretion in the rabbit

The insulin-secretional effect of arginine administrated to rabbits either intravenously or via alimentary tract was measured. Arginine stimulatory effect on insulin secretion was found after both ways of amino acid introduction, however, the extent of the stimulation depended upon the route of administration, with intravenous route being four times more effective than the oral one. This difference may depend on the small susceptibility to food stimulators of the herbivorous animals.