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Relationship between compliance with management target values and renal prognosis in multidisciplinary care for
Yoshihiko Imamura1, Yasunori Takahashi2, Takato Takeuchi3
1Department of Nephrology, Nissan Tamagawa Hospital, 4-8-1 Seta Setagaya-ku, Tokyo, 158-0095, Japan. yoshihiko.imamura@gmail.com.
Insights
Multidisciplinary care (MDC) improves chronic kidney disease (CKD) management by increasing adherence to treatment targets. This enhanced adherence leads to better renal survival rates and delayed dialysis initiation in CKD patients.
Area of Science:
- Nephrology
- Public Health
- Internal Medicine
Background:
- Multidisciplinary care (MDC) is recognized as essential for managing chronic kidney disease (CKD).
- The impact of MDC on achieving guideline-recommended management targets in CKD patients requires further investigation.
- This study aimed to elucidate the relationship between MDC, target value compliance, and renal prognosis in CKD outpatients.
Purpose of the Study:
- To assess the effect of multidisciplinary care (MDC) on patient compliance with chronic kidney disease (CKD) management targets.
- To determine the association between improved target value achievement and renal outcomes, including dialysis initiation and survival rates.
Main Methods:
- A cohort of 255 pre-dialysis CKD outpatients receiving MDC was analyzed.
- Achievement rates for blood pressure, hemoglobin, uric acid, LDL cholesterol, and HbA1c were compared pre- and post-MDC (12 months).
- Renal survival and dialysis initiation rates were evaluated based on categorized achievement rates post-MDC.
Main Results:
- Overall target achievement rate significantly increased from 62.8% to 69.1% after MDC.
- Higher achievement rates correlated with lower dialysis initiation rates (e.g., 8.2% for the highest group vs. 72.7% for the lowest).
- Significantly improved renal survival rates were observed with higher achievement levels.
Conclusions:
- MDC effectively enhances patient compliance with CKD management target values.
- Improved adherence to treatment targets through MDC is associated with better renal prognosis and delayed dialysis initiation.
Background:
Although multidisciplinary care (MDC) is necessary for controlling chronic kidney disease (CKD), its impact on compliance with management target values in the CKD guidelines remains unclear. This study was designed to clarify the relationship between compliance with management target values and renal prognosis in CKD outpatients who received MDC.
Methods:
There were 255 outpatients with pre-dialysis CKD who received MDC. Achievement rates of systolic, and diastolic blood pressure, hemoglobin, uric acid, low-density lipoprotein cholesterol, and hemoglobin A1c values determined according to CKD guidelines were compared before and 12 months after MDC. In addition, after dividing achievement rates of the target values at 12 months after MDC into four groups (A < 30% ≤ B < 60% ≤ C < 80% ≤ D), dialysis initiation and renal survival rates were compared.
Results:
There was a significant increase in the overall achievement rate from 62.8 to 69.1% (p < 0.001). The higher the achievement rate after MDC, the lower the dialysis initiation rate (A 72.7%, B 35.3%, C 20.5%, D 8.2%, p < 0.001). There was also a significantly higher renal survival rate (p < 0.001). These findings suggest that MDC for CKD raised awareness of health literacy, and improved the achievement rate of target values. Furthermore, the higher the achievement rate, the later the initiation of dialysis, which led to improvement of renal survival.
Conclusions:
MDC can improve compliance with management target values for CKD, suggesting that it may improve renal prognosis.
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