Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents01:18

Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents

215
Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
215
Bacterial Phylum Chlamydiae01:29

Bacterial Phylum Chlamydiae

137
The phylum Chlamydiae or Chlamydiota is composed of a single order, Chlamydiales. This phylum consists entirely of obligate intracellular parasites that infect eukaryotic hosts. While human pathogens within this group have been studied extensively, the phylum encompasses many species capable of interacting with various eukaryotic organisms. Members of Chlamydiae are typically small cocci, approximately 0.5 μm in diameter, and exhibit a distinctive developmental cycle. As is characteristic...
137
Stringent Response in E. coli01:23

Stringent Response in E. coli

68
Bacterial growth is closely tied to nutrient availability, with cells proliferating exponentially under favorable conditions and entering a stationary phase when resources become scarce. This transition is mediated by a regulatory mechanism known as the stringent response, which allows bacteria to adapt to nutrient deprivation by modulating gene expression and metabolic activity.During nutrient scarcity, intracellular amino acid levels decline. It results in the accumulation of uncharged tRNAs...
68
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

436
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
436
Bacterial Phylum Proteobacteria01:26

Bacterial Phylum Proteobacteria

195
Proteobacteria, one of the largest and most diverse bacterial phyla, encompasses a wide range of Gram-negative bacteria distinguished by their outer membrane composed of lipopolysaccharides. These microorganisms exhibit various metabolic capabilities, including phototrophy, chemolithotrophy, and heterotrophy, and thrive in diverse environments from soil to aquatic systems and host-associated niches. The phylum is divided into six classes: Alphaproteobacteria, Betaproteobacteria,...
195
Diversity of Protists I01:15

Diversity of Protists I

193
Excavata is a diverse group of protists that includes both chemoorganotrophic and phototrophic species, with some thriving in anaerobic environments. Among the key groups within Excavata are diplomonads and parabasalids, which are flagellated protists that lack mitochondria and chloroplasts. These microorganisms typically inhabit anoxic environments, such as the intestines of animals, where they exist either symbiotically or as parasites, relying on fermentation for energy production. Some...
193

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Open Diagnostic Reader (ODR): An affordable, modular 3D-printed platform for standardized imaging and quantitative analysis of rapid diagnostic tests.

HardwareX·2026
Same author

Estimating the Transmission Potential of Symptomatic and Asymptomatic Cholera Cases from Household Microbiological and Clinical Data.

The Journal of infectious diseases·2026
Same author

Quantifying relative health impact across Gavi, the Vaccine Alliance's portfolio in 117 countries at the subregional level: a modelling study.

Lancet (London, England)·2026
Same author

Cholera surveillance time series in Africa between 2010 and 2023.

Gates open research·2026
Same author

When mpox is not mpox: varicella and measles in DR Congo.

The Lancet. Infectious diseases·2026
Same author

Long-Term Antibody Responses to <i>Vibrio cholerae</i> Across Natural Infection, Vaccination, and Challenge: A Systematic Review.

medRxiv : the preprint server for health sciences·2026

Related Experiment Video

Updated: Sep 27, 2025

Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates
07:58

Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates

Published on: May 30, 2017

11.2K

Cholera.

Suman Kanungo1, Andrew S Azman2, Thandavarayan Ramamurthy1

  • 1National Institute of Cholera and Enteric Diseases, Kolkata, India.

Lancet (London, England)
|April 10, 2022
PubMed
Summary
This summary is machine-generated.

Cholera, a severe diarrheal disease caused by Vibrio cholerae, requires prompt rehydration. Global efforts focus on vaccination and improved sanitation to reduce deaths and eliminate transmission by 2030.

More Related Videos

Determination of Tolerable Fatty Acids and Cholera Toxin Concentrations Using Human Intestinal Epithelial Cells and BALB/c Mouse Macrophages
09:39

Determination of Tolerable Fatty Acids and Cholera Toxin Concentrations Using Human Intestinal Epithelial Cells and BALB/c Mouse Macrophages

Published on: May 30, 2013

10.1K
Quantifying Vibrio cholerae Colonization and Diarrhea in the Adult Zebrafish Model
08:03

Quantifying Vibrio cholerae Colonization and Diarrhea in the Adult Zebrafish Model

Published on: July 12, 2018

8.6K

Related Experiment Videos

Last Updated: Sep 27, 2025

Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates
07:58

Laboratory Techniques Used to Maintain and Differentiate Biotypes of Vibrio cholerae Clinical and Environmental Isolates

Published on: May 30, 2017

11.2K
Determination of Tolerable Fatty Acids and Cholera Toxin Concentrations Using Human Intestinal Epithelial Cells and BALB/c Mouse Macrophages
09:39

Determination of Tolerable Fatty Acids and Cholera Toxin Concentrations Using Human Intestinal Epithelial Cells and BALB/c Mouse Macrophages

Published on: May 30, 2013

10.1K
Quantifying Vibrio cholerae Colonization and Diarrhea in the Adult Zebrafish Model
08:03

Quantifying Vibrio cholerae Colonization and Diarrhea in the Adult Zebrafish Model

Published on: July 12, 2018

8.6K

Area of Science:

  • Infectious Diseases
  • Epidemiology
  • Microbiology

Background:

  • Cholera, caused by toxigenic Vibrio cholerae O1 or O139, is a global threat originating from the Bay of Bengal, causing severe diarrheal disease.
  • Seven pandemics have occurred over the past two centuries, highlighting the historical and ongoing impact of this infectious disease.

Purpose of the Study:

  • To provide a comprehensive overview of cholera, including its pathogenesis, natural history, bacteriology, and epidemiology.
  • To highlight recent advancements in molecular epidemiology, immunology, and vaccine development for cholera control.

Main Methods:

  • Review of existing literature and data on cholera.
  • Analysis of progress in global cholera control strategies and initiatives since 2014.
  • Examination of the Global Task Force on Cholera Control's roadmap and objectives.

Main Results:

  • Significant progress has been made in understanding cholera's molecular epidemiology and immunology.
  • Vaccine development and deployment have advanced, contributing to control efforts.
  • National cholera control strategies are being developed and implemented in several countries.

Conclusions:

  • Cholera remains a significant public health challenge requiring sustained global efforts.
  • The global roadmap aims to reduce cholera deaths by 90% and eliminate local transmission in 20 countries by 2030 through integrated interventions.
  • Continued focus on vaccination, water, sanitation, and hygiene (WASH) is crucial for cholera elimination.