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Perioperative opioid use in paediatric inguinal hernia patients: A systematic review and retrospective audit of
Isabel C Hageman1, Melissa Y Tien2, Misel Trajanovska3
1Murdoch Children's Research Institute, 50 Flemington Road, Parkville, Victoria 3052, Australia; Faculty of Medicine, Utrecht University, Utrecht, the Netherland.
Insights
Opioid prescribing for pediatric inguinal hernia surgery varies widely. At The Royal Children
Area of Science:
- Pediatric Surgery
- Pain Management
- Pharmacology
Background:
- Opioids are crucial for pediatric postoperative pain, yet their use is understudied.
- This study investigates perioperative opioid prescribing for pediatric inguinal hernia patients.
- Practices were examined in existing literature and at The Royal Children's Hospital (RCH).
Purpose of the Study:
- To describe current opioid prescribing patterns for pediatric inguinal hernia repair.
- To compare literature-based practices with institutional data from RCH.
- To identify factors influencing opioid use in this patient population.
Main Methods:
- A systematic review of English articles (2009-2019) on pediatric inguinal hernia patients receiving opioids.
- A retrospective audit of 150 pediatric inguinal hernia patients at RCH.
- Collection of demographic, surgical, and analgesic data from electronic medical records.
Main Results:
- Fifteen studies (n=1166) showed wide variation in postoperative opioid use (3.33-100%).
- At RCH, 17.3% of 150 patients received postoperative opioids, primarily fentanyl and oxycodone.
- Older age, female sex, and lack of regional anesthesia correlated with increased opioid use; no discharge prescriptions were given.
Conclusions:
- Significant variability exists in pediatric inguinal hernia opioid prescribing.
- Opioid use in the postoperative period at RCH was infrequent.
- Further research is needed to standardize safe and effective pediatric pain management.
Background:
Opioids play a major role in postoperative pain management in children, but their administration remains an under investigated topic. This study aimed to describe perioperative opioid prescribing practices for paediatric inguinal hernia patients in the literature and at The Royal Children's Hospital (RCH) in Melbourne, Australia.
Material/Method:
A systematic review of English articles (published from 2009 to 2019) was conducted on paediatric (0-18y) inguinal hernia patients who received a postoperative or discharge opioid prescription, or both. The review was combined with a retrospective audit of RCH patients. Demographic, surgical, and analgesic details were collected from the electronic medical records.
Results:
Fifteen studies (n = 1166; combined mean age 4.93y) met the systematic review criteria. The percentage of patients receiving opioids postoperatively overall ranged from 3.33-100%, and doses ranged from 0.07 to 0.35 mg/kg oMEDD. At the RCH, perioperative opioid use was analyzed from 150 inguinal hernia patients (male - 113, median age - 3 months old). Postoperatively, 26 (17.3%) patients received opioids. The most commonly administered opioids were fentanyl (0.04-0.60 mg/kg oMEDD) in the post anaesthesia care unit and oxycodone (0.14-0.40 mg/kg oMEDD) in the first 24 h postoperatively. Older age at surgery, female sex and absence of regional anaesthesia were significantly associated with higher risk of total opioid use. No patients received an opioid prescription at discharge.
Conclusion:
There is demonstratable variability in opioid prescribing practices for paediatric inguinal hernia patients as described in the literature. At our institution opioids were not used frequently in postoperative period.
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