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Mortality outcomes and 30-day readmissions associated with coronary artery aneurysms; a National Database Study

Tanveer Mir1, Mohammed Uddin2, Khalid Changal3

  • 1Internal Medicine Wayne State University, Detroit, MI, USA; Internal Medicine, Baptist Health System, Montgomery, AL, USA.

International Journal of Cardiology
|April 10, 2022
PubMed

Insights

Coronary artery aneurysm (CAA) is rare, affecting 0.141% of patients undergoing coronary angiography. While overall mortality is similar, CAA patients with acute coronary syndrome (ACS) face significantly higher risks and readmission rates.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Epidemiology

Background:

  • Limited data exists on the prevalence and outcomes of coronary artery aneurysm (CAA) in the United States.
  • Coronary artery aneurysms are uncommon vascular anomalies.
  • Understanding CAA epidemiology is crucial for patient management.

Purpose of the Study:

  • To determine the prevalence and outcomes of coronary artery aneurysm (CAA).
  • To analyze trends in CAA and associated acute coronary syndrome (ACS) over time.
  • To investigate the impact of percutaneous coronary intervention (PCI) on mortality in CAA patients.

Main Methods:

  • Analysis of the National Readmissions Database (NRD) from 2012-2018.
  • Inclusion of hospitalizations related to coronary angiography (CA).
  • Comparison of outcomes between patients with and without CAA, stratified by ACS status.

Main Results:

  • CAA prevalence was 0.141% among 6.8 million CA hospitalizations.
  • CAA patients with ACS exhibited higher mortality, cardiogenic shock, and ventricular arrhythmias.
  • PCI showed no significant association with reduced mortality in CAA patients; readmission rates were lower for CAA patients.

Conclusions:

  • Coronary artery aneurysm is an uncommon finding on coronary angiography.
  • The increased mortality associated with ACS in CAA patients necessitates further investigation.
  • The rising trend of CAA with ACS warrants continued research and clinical attention.
Abstract

Keywords:
Coronary angiographyCoronary artery aneurysmCoronary artery dissectionCoronary ectasiaPCIPrevalence

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