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Updated: Sep 27, 2025

Multifractal Spectrum Analysis for Assessing Pulmonary Nodule Malignancy
Published on: January 10, 2025
Multimodality management of focal nodular hyperplasia
Damján Pekli1, Bálint Kokas1, Dávid Bárdos1
11 Semmelweis Egyetem, Általános Orvostudományi Kar, Sebészeti, Transzplantációs és Gasztroenterológiai Klinika Budapest, Üllői út 78., 1082 Magyarország.
Focal nodular hyperplasia (FNH), a common benign liver mass, can be managed with observation, transarterial embolization (TAE), or surgical resection. Treatment choice depends on symptom presence and surgical risk.
Area of Science:
- Hepatology
- Interventional Radiology
- Surgical Oncology
Background:
- Focal nodular hyperplasia (FNH) is the second most common benign liver mass, with treatment recommendations varying.
- Current guidelines suggest surgical removal as a relative indication for FNH.
- Diverse treatment modalities exist for managing FNH.
Observation:
- A 40-year-old woman with FNH underwent transarterial embolization (TAE) due to high surgical risk, achieving symptom resolution.
- A 25-year-old woman with symptomatic FNH causing vena cava compression underwent successful liver resection.
Findings:
- Transarterial embolization (TAE) can be effective for FNH, particularly in symptomatic cases or when surgical resection poses a high risk.
- Laparatic resection is a suitable primary treatment for lower-risk FNH patients.
- Long-term follow-up may suffice for asymptomatic FNH.
Implications:
- This study highlights tailored treatment strategies for FNH based on individual patient factors.
- It emphasizes the efficacy of TAE as an alternative or adjunct to surgery for FNH.
- The findings support personalized management approaches for benign liver tumors.
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