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Outcomes of Sarcopenia Treatment for Malignant Bone and Soft Tissue Tumors in Elderly Patients
Yoshitaka Ban1, Hoshi Manabu1, Naoto Oebisu1
1Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.
Background/Aim:
We determined the impact of sarcopenia on the treatment outcomes of malignant bone and soft tissue tumors in elderly patients.
Patients And Methods:
We retrospectively reviewed 76 patients (age ≥65 years) who were treated for malignant bone and soft tissue tumors. Sarcopenia was assessed by measuring the cross-sectional area of the psoas muscles at the L3 vertebra from preoperative computed tomography images and categorized using the total psoas area/m (TPA/m ) ≤5.0 cm /m . The patients' clinical data were then evaluated.
Results:
The operation time, length of hospital stay, and median overall survival were not different between the sarcopenia (n=41) and no-sarcopenia (n=35) groups. The local recurrence rate (p=0.01) and incidence of postoperative complications (p=0.02) significantly differed between both groups. The TPA/m of both groups significantly decreased at the final follow-up.
Conclusion:
Sarcopenia negatively influenced wound healing and local recurrence, and was significantly exacerbated postoperatively in all elderly patients.
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