Related Experiment Video

Updated: Aug 12, 2026

A Fluorescence-based Exonuclease Assay to Characterize DmWRNexo, Orthologue of Human Progeroid WRN Exonuclease, and Its Application to Other Nucleases
06:10

A Fluorescence-based Exonuclease Assay to Characterize DmWRNexo, Orthologue of Human Progeroid WRN Exonuclease, and Its Application to Other Nucleases

Published on: December 23, 2013

uvrC gene function has no specific role in repair of N-2-aminofluorene adducts

M Bichara, R P Fuchs

    Journal of Bacteriology
    |January 1, 1987
    PubMed

    More Related Videos

    Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair10:59

    Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair

    Published on: May 24, 2017

    Studying Ribonucleotide Incorporation: Strand-specific Detection of Ribonucleotides in the Yeast Genome and Measuring Ribonucleotide-induced Mutagenesis09:04

    Studying Ribonucleotide Incorporation: Strand-specific Detection of Ribonucleotides in the Yeast Genome and Measuring Ribonucleotide-induced Mutagenesis

    Published on: July 26, 2018

    Related Concept Videos

    Nucleotide Excision Repair01:08

    Nucleotide Excision Repair

    Overview
    Overview of DNA Repair02:25

    Overview of DNA Repair

    In order to be passed through generations, genomic DNA must be undamaged and error-free. However, every day, DNA in a cell undergoes several thousand to a million damaging events by natural causes and external factors. Ionizing radiation such as UV rays, free radicals produced during cellular respiration, and hydrolytic damage from metabolic reactions can alter the structure of DNA. Damages caused include single-base alteration, base dimerization, chain breaks, and cross-linkage.
    Chemically...
    Nucleotide Excision Repair01:08

    Nucleotide Excision Repair

    Overview
    Base-pairing and DNA Repair02:27

    Base-pairing and DNA Repair

    Erwin Chargaff’s rules on DNA equivalence paved the way for the discovery of base pairing in DNA. Chargaff’s rules state that in a double-stranded DNA molecule,
    Overview of DNA Repair02:25

    Overview of DNA Repair

    In order to be passed through generations, genomic DNA must be undamaged and error-free. However, every day, DNA in a cell undergoes several thousand to a million damaging events by natural causes and external factors. Ionizing radiation such as UV rays, free radicals produced during cellular respiration, and hydrolytic damage from metabolic reactions can alter the structure of DNA. Damages caused include single-base alteration, base dimerization, chain breaks, and cross-linkage.
    Chemically...
    Nucleotide Excision Repair01:38

    Nucleotide Excision Repair

    DNA Distortion and Damage
    Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...