Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Endocarditis I: Introduction

Endocarditis I: Introduction

Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...

Bacterial Phylum Spirochaetes

Bacterial Phylum Spirochaetes

Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased...

Acute Pyelonephritis I: Introduction

Acute Pyelonephritis I: Introduction

Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...

Rheumatic Heart Disease I: Introduction

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...

Acute Pyelonephritis II: Diagnostic Studies and Management

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Initial Experience with Robotic-Assisted CT-Guided Ablation: Analysis from a Single Center's Learning Curve in the First 54 Patients.

Journal of vascular and interventional radiology : JVIR·2026

Same author

Endovascular Superior Vena Cava Reconstruction for the Treatment of Symptomatic Downhill Esophageal Varices.

Journal of vascular and interventional radiology : JVIR·2025

Same author

An Arterial Anastomosis Stenosis Used in Lieu of Banding to Prevent Dialysis Access Steal Syndrome.

Cureus·2022

Same author

First Reported Case of Femoral Facial Syndrome in an Adult: Esophageal Adenocarcinoma as a Progressive Gastrointestinal Manifestation.

Cureus·2022

Same author

Combat Radiology: Imaging 3.0 in Faraway Places.

Journal of the American College of Radiology : JACR·2014

Same author

Research reporting standards for endovascular treatment of pelvic venous insufficiency.

Journal of vascular and interventional radiology : JVIR·2010

Search research articles

Related Experiment Video

Updated: Sep 27, 2025

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections

Published on: February 2, 2024

Abiotrophia Causing Prosthetic Joint Septic Arthritis.

Juliana N Young¹, John York²

¹Department of Internal Medicine, Burrell College of Osteopathic Medicine, Las Cruces, USA.

|April 11, 2022

Summary

This summary is machine-generated.

A patient with Charcot-Marie-Tooth disease experienced a rare knee infection caused by Abiotrophia defectiva. Despite initial treatment, a secondary Enterobacter cloacae infection developed, highlighting complex post-surgical challenges.

Keywords:

16s rdna pcr abiotrophia defectiva charcot marie tooth disease enterobacter cloacae prosthetic joint infection

More Related Videos

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Published on: December 3, 2017

A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials

A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials

Published on: March 3, 2023

Related Experiment Videos

Last Updated: Sep 27, 2025

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections

Published on: February 2, 2024

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction

Published on: December 3, 2017

A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials

A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials

Published on: March 3, 2023

Area of Science:

Orthopedic Surgery
Infectious Diseases
Microbiology

Background:

A 71-year-old male with Charcot-Marie-Tooth disease type 2 presented with left knee pain and swelling.
The patient had a history of bilateral total knee replacements and a prior left knee revision for infection.

Observation:

Joint aspiration revealed a culture-positive and 16S recombinant DNA (rDNA) sequence-positive result for Abiotrophia defectiva.
The patient underwent left total knee extraction with a temporary antibiotic spacer and received six weeks of intravenous ceftriaxone.

Findings:

Initial treatment successfully cleared the Abiotrophia defectiva infection.
The patient later developed complications, including a subsequent Enterobacter cloacae infection.

Implications:

This case underscores the challenges in managing complex joint infections, particularly in patients with underlying neurological conditions.
Recurrent and secondary infections require vigilant monitoring and adaptable treatment strategies.
Further research into Abiotrophia defectiva and Enterobacter cloacae in prosthetic joint infections is warranted.