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Anesthetic Challenges Posed by Heavy Kratom Users.

Elisa Lund1, Aaron B Low2, Jennifer D Allan1

  • 1Anesthesiology, University of North Carolina, Chapel Hill, USA.

Cureus
|April 11, 2022
PubMed
Summary
This summary is machine-generated.

Kratom, a popular herbal supplement, poses anesthetic challenges due to its stimulant and opioid receptor interactions. This case report details difficulties encountered with a heavy kratom user during anesthesia.

Keywords:
alpha-2 agonismanesthesiakratomopioidspain managementsubstance usewithdrawal

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Area of Science:

  • Pharmacology
  • Anesthesiology
  • Herbal Medicine

Background:

  • Kratom (Mitragyna speciosa) is a Southeast Asian herb gaining popularity in the US.
  • It contains psychoactive compounds affecting opioid, alpha-2, and serotonergic receptors.
  • Kratom is used for stimulant effects, pain, anxiety, and opioid withdrawal management.

Observation:

  • Limited data exists on habitual kratom use's impact during anesthesia.
  • This case report focuses on a patient with heavy kratom consumption.
  • Anesthetic management challenges were observed in this individual.

Findings:

  • Heavy kratom use can complicate anesthetic procedures.
  • Specific receptor interactions may lead to unpredictable patient responses.
  • Further research is needed to understand these anesthetic implications.

Implications:

  • Anesthesiologists must be aware of potential kratom interactions.
  • Preoperative assessment should include detailed substance use history.
  • Clinical guidelines may need updating to address kratom use in surgical patients.