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Updated: Sep 27, 2025

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Published on: February 7, 2022
Successful Orthotopic Heart Transplantation With Positive Crossmatch in a Hyperimmunized Child on Mechanical
S Pawlak1, J E Śliwka2, A Wierzyk2
1Department of Cardiac, Vascular and Endovascular Surgery and Transplantology, Medical University of Silesia, Silesian centre for Heart Diseases, Zabrze, Poland.
Abstract:
In the pediatric population there is a shortage in the number of hearts available for transplantation. However, sometimes a heart transplant is urgently required to save lives. The problem arises when the patient is hyperimmunized and there is a positive crossmatch with the only available donor. We present such a case of a 9-year-old patient with dilated cardiomyopathy on ventricular assist device, in whom it was possible to perform a successful HT and also apply a successive prevention against graft rejection.
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