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Paediatric cholestatic liver disorders for the adult gastroenterologist: a practical guide

Claire Kelly1, Jeremy Shanika Nayagam1, Stamatina Vogli1

  • 1Institute of Liver Studies, King's College Hospital, London, UK.

Frontline Gastroenterology
|April 11, 2022
PubMed

Insights

As more children with cholestatic liver diseases survive, adult physicians need expertise in managing these complex conditions. This review guides adult care for pediatric liver diseases.

Area of Science:

  • Hepatology
  • Pediatric Gastroenterology
  • Internal Medicine

Background:

  • Improved outcomes for pediatric cholestatic liver diseases necessitate adult care.
  • Adult physicians require specialized knowledge for these historically pediatric conditions.

Purpose of the Study:

  • To provide an overview of common pediatric cholestatic liver diseases.
  • To outline clinical manifestations, complications, and management for adult care.

Main Methods:

  • Literature review of pediatric cholestatic liver diseases.
  • Synthesis of current management strategies for adult patients.

Main Results:

  • Identification of key pediatric cholestatic liver diseases.
  • Summary of unique management considerations for each condition in adults.

Conclusions:

  • Adult care providers need to develop expertise in managing transitioned pediatric liver disease patients.
  • Effective ongoing care requires understanding specific disease manifestations and complications.

Keywords:
cholestasischolestatic liver diseasespaediatric liver disease

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