Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Opioid Analgesics: Synthetic and Semisynthetic Opioids01:15

Opioid Analgesics: Synthetic and Semisynthetic Opioids

461
Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
461
Opioid Analgesics: Morphine and Other Natural Cogeners01:20

Opioid Analgesics: Morphine and Other Natural Cogeners

401
Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
401
Analgesia and Pain Management01:25

Analgesia and Pain Management

849
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
849
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

205
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
205
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

35
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
35
Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents01:17

Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents

352
Diarrhea, a condition marked by frequent loose or watery bowel movements, can be triggered by multiple factors such as viral or bacterial infections, food intolerances, anxiety, medications, and digestive disorders. Symptoms may include abdominal pain, bloating, nausea, and cramping. Severe or prolonged diarrhea can lead to complications like electrolyte imbalances, malnutrition, and dehydration if left untreated.
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...
352

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Standardized Knee Meniscus MRI Reporting: An Interdisciplinary Delphi Consensus.

Radiology·2026
Same author

Standardized MRI nomenclature for knee meniscal lesions: SSR consensus panel report.

Skeletal radiology·2026
Same author

Associations Between Patient Characteristics and Cartilage T1ρ Relaxation Times Vary Over Time Following Patellar Dislocation.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society·2026
Same author

Intraoperative Manual Resistance and Direct Intra-articular Visualization Maneuvers for Anterior Cruciate Ligament Reconstruction: A Retrospective Cohort Study.

The American journal of sports medicine·2026
Same author

A Systematic Review of the Impact of Patient Pain Catastrophizing and Resiliency on Patient Reported Outcomes in Hip Arthroscopy for Femoroacetabular Impingement.

Sports medicine and arthroscopy review·2026
Same author

Having a Revision ACL Reconstruction Is Worse Than Tearing the Contralateral ACL and Undergoing Reconstruction: A MOON Cohort Study.

The American journal of sports medicine·2026

Related Experiment Video

Updated: Sep 27, 2025

Author Spotlight: Minimally Invasive Ultrasound-Guided Acupotomy in Knee Osteoarthritis Treatment
04:57

Author Spotlight: Minimally Invasive Ultrasound-Guided Acupotomy in Knee Osteoarthritis Treatment

Published on: April 26, 2024

734

Opioid Use After Simple Arthroscopic Knee Surgery.

Michael J Scarcella1, Lutul D Farrow1, Morgan H Jones2

  • 1Cleveland Clinic Orthopaedic and Rheumatologic Institute, Cleveland, Ohio, USA.

The American Journal of Sports Medicine
|April 11, 2022
PubMed
Summary
This summary is machine-generated.

Opioids are frequently overprescribed after knee arthroscopy. Researchers suggest prescribing 4 opioid pills post-surgery, as preoperative pain predicts higher consumption.

Keywords:
opioidspainpatient-reported outcomespill consumptionsimple knee arthroscopy

More Related Videos

Knee Arthrocentesis in Adults
04:41

Knee Arthrocentesis in Adults

Published on: February 25, 2022

8.0K
The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve
09:51

The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve

Published on: September 7, 2022

3.1K

Related Experiment Videos

Last Updated: Sep 27, 2025

Author Spotlight: Minimally Invasive Ultrasound-Guided Acupotomy in Knee Osteoarthritis Treatment
04:57

Author Spotlight: Minimally Invasive Ultrasound-Guided Acupotomy in Knee Osteoarthritis Treatment

Published on: April 26, 2024

734
Knee Arthrocentesis in Adults
04:41

Knee Arthrocentesis in Adults

Published on: February 25, 2022

8.0K
The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve
09:51

The Transition to an Anterior-Based Muscle Sparing Approach Improves Early Postoperative Function but is Associated with a Learning Curve

Published on: September 7, 2022

3.1K

Area of Science:

  • Orthopaedic Surgery
  • Pain Management
  • Pharmacology

Background:

  • Evidence-based prescribing guidelines for postoperative opioids in orthopaedics are scarce.
  • Opioid overprescription is common following simple knee arthroscopy procedures.

Purpose of the Study:

  • To evaluate opioid consumption patterns after simple arthroscopic knee surgery.
  • To identify risk factors associated with high postoperative opioid use.

Main Methods:

  • A prospective cohort study of 174 patients undergoing simple arthroscopic knee surgery.
  • Patients received 10 opioid pills; consumption was categorized into low (0-2) and high (3+).
  • Risk factors including demographics, baseline pain (KOOS Pain), and mental health were analyzed.

Main Results:

  • Opioid consumption varied widely, with a median of 2 pills.
  • 59% of patients were low consumers, while 41% were high consumers.
  • Preoperative pain (KOOS Pain score) significantly predicted higher postoperative opioid consumption (OR, 0.97; P = .003).

Conclusions:

  • Opioids are overprescribed after simple arthroscopic knee surgery.
  • A recommendation of 4 opioid pills post-surgery is suggested.
  • Preoperative pain is a key factor influencing postoperative opioid needs.