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How Should Representation of Subjects With LEP Become More Equitable in Clinical Trials?
Jonathan Alhalel1, Nicolás Francone2, Sharon Post3
1Fourth-year medical student at the Northwestern University Feinberg School of Medicine in Chicago, Illinois.
Abstract:
Underrepresentation of individuals with limited English proficiency (LEP) who speak Spanish is ongoing in phase 3 biomedical clinical trials and exacerbates health inequity. This article suggests strategies for increasing representation of Spanish speakers in clinical rials by emphasizing the importance of early engagement with Spanish language communities, inclusive participant recruitment, and collaborative trial design and implementation. Although investigators and institutions administering government-funded research must meet federal requirements for language assistance, journal editors, peer reviewers, institutional review board members, academic health centers, and all beneficiaries of the biomedical and behavioral research enterprise in the United States must motivate linguistic inclusion.
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