Multifunctionalized Mesostructured Silica Nanoparticles Containing Mn2 Complex for Improved Catalase-Mimicking...

We report the synthesis of a hybrid nanocatalyst obtained through the immobilization of bio-inspired [{Mn(bpy)(H₂O)}(µ-2-MeC₆H₄COO)₂(µ-O){Mn(bpy)(NO₃)}]NO₃ compound into functionalized, monodispersed, mesoporous silica nanoparticles. The in situ dual functionalization sol-gel strategy adopted here leads to the synthesis of raspberry-shaped silica nanoparticles of ca. 72 nm with a large open porosity with preferential localization of 1,4-pyridine within the pores and sulfobetaine zwitterion on the nanoparticles' periphery. These nano-objects exhibit improved catalase-mimicking activity in water thanks to the encapsulation/immobilization of the catalytic active complex and high colloidal stability in water, as demonstrated through the dismutation reaction of hydrogen peroxide.