Related Experiment Video
Updated: Sep 27, 2025
09:39
A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries
Published on: December 27, 2016
18.0K
A Blockchain Secured Pharmaceutical Distribution System to Fight Counterfeiting.
Kavyan Zoughalian1, Jims Marchang2, Bogdan Ghita3
1Computing Department, Sheffield Hallam University, Sheffield S1 1WB, UK.
Summary
Blockchain technology enhances pharmaceutical supply chain transparency and drug security. This study proposes a novel prototype using zero-knowledge proofs and a Markov model to improve data integrity and node reliability, addressing current system limitations.
Area of Science:
- Pharmaceutical supply chain management
- Blockchain technology applications
- Information security in healthcare
Background:
- Drug counterfeiting is a significant global issue.
- Current pharmaceutical distribution systems lack transparency.
- Blockchain technology offers potential solutions for supply chain integrity.
Purpose of the Study:
- To explore blockchain-based solutions for pharmaceutical distribution.
- To identify limitations in existing blockchain proposals, specifically data secrecy and node reputation.
- To propose a novel prototype addressing these identified gaps.
Main Methods:
- Literature review of current blockchain solutions for pharmaceutical distribution.
- Development of a prototype utilizing zero-knowledge proof for data integrity.
- Implementation of a Markov model to assess and track node reputation scores for reliable decision-making.
Main Results:
- The proposed prototype enhances data confidentiality, integrity, and availability.
- Zero-knowledge proofs ensure the integrity of distributed data.
- The Markov model effectively predicts node reliability for consensus decision-making, improving system security.
Conclusions:
- The decision-making protocol is crucial for reliable blockchain-based distribution systems.
- Pharmaceutical distribution systems should adopt relevant protocols for blockchain implementation.
- Further research is recommended to enhance the performance and reliability of blockchain in distribution systems.
More Related Videos
Related Concept Videos
01:29Issues And Trends In Healthcare Delivery System
5.9K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.9K
01:02Prescription, Nonprescription and Orphan Drugs
874
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
874
01:21Drug Distribution: Tissue Binding
3.3K
Upon entering the systemic circulation, drugs can distribute into the interstitial and intracellular fluid of various tissue cells. This distribution is facilitated by the binding of drugs to different cellular components within tissues, which may lead to drug accumulation in specific areas. Drugs bound to tissue components serve as reservoirs that release free drugs back into the system, prolonging the drug's overall action. However, this accumulation can also result in local toxicity.
For...
For...
3.3K
01:11Drug Distribution: Overview
375
Drug distribution within the body is a dynamic process involving the movement of a drug in two directions across various compartments: from the bloodstream into tissues (tissue uptake) and from tissues back into the bloodstream (tissue release or redistribution). This process is passive and primarily driven by two variables: the concentration gradient between the bloodstream and the extravascular tissues and the drug's ability to cross the cell membrane.
Initially, the free drug in the...
Initially, the free drug in the...
375
01:25Drug Distribution: Volume of Distribution
6.1K
The volume of distribution refers to the theoretical volume necessary to contain the entire amount of an administered drug at the same concentration observed in the blood plasma. The body's intracellular fluid compartment, which makes up two-thirds of the total body water, is contrasted with the extracellular fluid compartment—comprising plasma and interstitial fluid—that accounts for one-third. The volume of distribution can vary depending on the characteristics of the drug.
6.1K
01:17Drug Nomenclature
2.4K
During the development of a new pharmaceutical, the manufacturer initially assigns a code name to the drug. Once approved, the drug receives a United States Adopted Name (USAN)—a generic, nonproprietary designation. Upon being listed in the United States Pharmacopeia, this nonproprietary name becomes the drug's official name. Additionally, the manufacturer assigns a proprietary name or trademark, which serves as the brand name under which the drug is marketed. It is worth noting that...
2.4K