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Related Concept Videos

Diversity of Protists I01:15

Diversity of Protists I

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Excavata is a diverse group of protists that includes both chemoorganotrophic and phototrophic species, with some thriving in anaerobic environments. Among the key groups within Excavata are diplomonads and parabasalids, which are flagellated protists that lack mitochondria and chloroplasts. These microorganisms typically inhabit anoxic environments, such as the intestines of animals, where they exist either symbiotically or as parasites, relying on fermentation for energy production. Some...
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Fungal Phylum Microsporidia01:28

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Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
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Diversity of Protists IV01:27

Diversity of Protists IV

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Amoebozoa represent a diverse group of terrestrial and aquatic protists that utilize lobe-shaped pseudopodia for locomotion and feeding. This characteristic differentiates them from the Rhizaria, which possess threadlike pseudopodia. The primary classifications within Amoebozoa include gymnamoebas, entamoebas, and the plasmodial and cellular slime molds. Phylogenetic evidence indicates that Amoebozoa diverged from a lineage that ultimately gave rise to fungi and animals.Gymnamoebas and...
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Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
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Related Experiment Video

Updated: Sep 27, 2025

Discovery of New Intracellular Pathogens by Amoebal Coculture and Amoebal Enrichment Approaches
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A rare case of extraintestinal amebiasis.

Bao Fu1, Jinjing Wang2, Xiaoyun Fu3

  • 1Department of Critical care Medicine, Affiliated Hospital of Zunyi Medical University, Dalian Road 149, Zunyi City, 563003, Guizhou, China.

BMC Infectious Diseases
|April 12, 2022
PubMed
Summary

Disseminated amoebiasis, caused by Entamoeba histolytica, is rare but deadly. This case highlights simultaneous infections in the lungs, urinary system, and brain, emphasizing the need for early diagnosis and treatment to improve patient outcomes.

Keywords:
AmebiasisCentral nervous systemPleuropulmonaryUrinary amoebiasis

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Area of Science:

  • Infectious Diseases
  • Parasitology
  • Clinical Medicine

Background:

  • Amoebiasis, caused by Entamoeba histolytica, is a rare parasitic infection in developed nations.
  • Extraintestinal spread via bloodstream can lead to severe organ involvement.
  • Simultaneous multiple organ infections are exceptionally uncommon.

Observation:

  • A rare case of simultaneous Entamoeba histolytica infection involving the pulmonary pleura, urinary system, and central nervous system is presented.
  • The patient underwent anti-amoeba therapy.
  • Despite treatment, the patient experienced a poor prognosis.

Findings:

  • Multiple extraintestinal amebic infections occurred without confirmed intestinal amebiasis or amebic liver abscess.
  • This presentation posed significant diagnostic challenges.
  • Disseminated amebiasis was associated with substantially increased mortality.

Implications:

  • Early diagnosis and prompt, appropriate treatment are crucial for reducing mortality in disseminated amebiasis.
  • This case underscores the diagnostic difficulties and poor prognosis associated with rare, widespread Entamoeba histolytica infections.
  • Further research into effective management strategies for disseminated amebiasis is warranted.