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[Hyperparathyroidism and pregnancy. Review of the literature]
This review of the literature includes 92 cases of hyperparathyroidism associated with pregnancy since 1930. Hyperparathyroidism is rare during pregnancy and often remains asymptomatic. Thus, a fetal death or an episode of neonatal tetany may reveal a maternal hyperparathyroidism. Determination of the calcium blood levels at the slighest maternal symptom, or a posteriori, in view of complications of pregnancy or in the neonatal period, must enable to entertain the diagnosis of this disease. If the diagnosis is made during pregnancy, the surgical treatment of choice is easier during the second trimester. Most frequently, the excision of a parathyroid adenoma responsible for the symptoms, prevents maternal and neonatal complications.
This review of the literature includes 92 cases of hyperparathyroidism associated with pregnancy since 1930. Hyperparathyroidism is rare during pregnancy and often remains asymptomatic. Thus, a fetal death or an episode of neonatal tetany may reveal a maternal hyperparathyroidism. Determination of the calcium blood levels at the slighest maternal symptom, or a posteriori, in view of complications of pregnancy or in the neonatal period, must enable to entertain the diagnosis of this disease. If the diagnosis is made during pregnancy, the surgical treatment of choice is easier during the second trimester. Most frequently, the excision of a parathyroid adenoma responsible for the symptoms, prevents maternal and neonatal complications.