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Updated: Sep 27, 2025

A Fish-feeding Laboratory Bioassay to Assess the Antipredatory Activity of Secondary Metabolites from the Tissues of Marine Organisms
Published on: January 11, 2015
New Bioactive Polyacetylenes from the Marine Sponge Petrosia sp
Xin-Lian Liu1, Ya-Fang Ding1, Shu-Ping Wang2
1School of Food and Pharmacy, Zhejiang Ocean University, Zhoushan, 316000, P. R. China.
Abstract:
Three new polyacetylenes, pellynols P (1), Q (2), and R (3) were isolated from the marine sponge Petrosia sp., along with the known compound pellynol H (4). Their structures were determined by analyses of extensive NMR, HR-MS, and ESI-MS/MS data. All compounds displayed potent cytotoxicities against human hepatocellular carcinoma HepG2, human melanoma A375, and human colorectal carcinoma HT29 cell lines with IC50 values at the range of 1.4-4.4 μM.
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