Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

WashU Epigenome Browser update 2022.

Daofeng Li1,2, Deepak Purushotham1,2, Jessica K Harrison1,2

  • 1Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.

Nucleic Acids Research
|April 12, 2022
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Differential cytokine architecture in patients treated with CART19 versus CART22.

Journal for immunotherapy of cancer·2026
Same author

Reliability Assessment of Metal Quantification in Formalin-fixed, Paraffin-embedded Human Liver Tissue for Studying Liver Diseases.

Research square·2026
Same author

Spatial transcriptomics reveals differences in bronchus-associated lymphoid tissue composition in stable and rejecting human lung allografts.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same author

How Drug-Drug Interaction Studies Inform Drug Labeling: A Survey of US Food and Drug Administration-Approved New Molecular Entities from 1998 to 2022.

Clinical pharmacology and therapeutics·2026
Same author

Distinct and shared synergistic effects of high-fat and high-iron diets on liver tumorigenesis and transcriptomic remodeling in mice.

bioRxiv : the preprint server for biology·2026
Same author

ToxiTaRGET: a multi-omics database for toxicant-responsive molecular targets.

Nature communications·2026
This summary is machine-generated.

The WashU Epigenome Browser offers an integrated panel for visualizing 1D, 2D, 3D, and 4D genomic data, enhancing epigenomic research efficiency. This tool supports diverse data types and serves as a foundation for other genomics platforms.

Area of Science:

  • Genomics
  • Bioinformatics
  • Computational Biology

Background:

  • The WashU Epigenome Browser is a web-based tool for exploring epigenomic datasets.
  • Recent renovations since 2018 have improved user interface and functionality for efficient data engagement.

Purpose of the Study:

  • Introduce a new integrated panel design for simultaneous interaction with 1D, 2D, 3D, and 4D genomic data.
  • Enhance visualization and analysis capabilities for diverse epigenomic datasets.

Main Methods:

  • Implemented an integrated panel design for multi-dimensional data visualization.
  • Developed a 3D viewer module for displaying chromatin structures.
  • Introduced 'Dynamic' tracks for animating time-series (4D) data.

Related Experiment Videos

Main Results:

  • Users can now interact with 1D, 2D, 3D, and 4D data within a single web page.
  • The browser visualizes 3D genome structures and animates time-series data for dynamic analysis.
  • Supports various data types including genomic features, numerical values, chromatin interactions, and microscopy imaging data.

Conclusions:

  • The enhanced WashU Epigenome Browser facilitates more efficient and effective epigenomic data exploration.
  • The integrated design and new features support advanced analysis of complex genomic and epigenomic data.
  • The browser serves as a versatile platform, underpinning other genomics tools and supporting large consortia data hubs.