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Related Experiment Video

Updated: Sep 27, 2025

Three-dimensional Optical-resolution Photoacoustic Microscopy
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Programmable Acoustic Delay-Line Enabled Low-Cost Photoacoustic Tomography System.

Daohuai Jiang, Hengrong Lan, Yiyun Wang

    IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
    |April 12, 2022
    PubMed
    Summary

    A new programmable acoustic delay-line (PADL) module reduces data acquisition costs and speeds up imaging for photoacoustic tomography (PAT). This innovation merges multiple signals, enabling faster, more affordable biomedical imaging.

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    Area of Science:

    • Biomedical imaging
    • Acoustic engineering
    • Optical physics

    Background:

    • Photoacoustic tomography (PAT) offers high optical contrast and acoustic penetration for biomedical imaging.
    • Current PAT systems face challenges with imaging speed and data acquisition costs, especially for high-fidelity image reconstruction.
    • Single-channel scanning is slow, while array-based systems require expensive data acquisition modules.

    Purpose of the Study:

    • To develop a cost-effective solution for accelerating photoacoustic tomography (PAT) imaging speed.
    • To reduce the data acquisition (DAQ) costs associated with array-based PAT systems.
    • To introduce a programmable acoustic delay-line (PADL) module for enhanced PAT performance.

    Main Methods:

    • Designed a programmable acoustic delay-line (PADL) module for bidirectional acoustic-electrical signal conversion.

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  • Integrated ultrasound transmission for precise time delay control within the acoustic delay-line.
  • Developed a programmable control unit to manage signal delays and merging of four PA signals into one output.
  • Implemented signal recovery in the digital domain post-data acquisition.

    • Main Results:

    • The PADL module successfully merged four photoacoustic (PA) signals into a single output, recoverable in the digital domain.
    • Imaging experiments with phantom and in vivo human finger demonstrated the feasibility of the PADL module.
    • The proposed module significantly reduces the overall cost of PAT systems.
    • Imaging speed was accelerated, and DAQ costs were lowered.

    Conclusions:

    • The programmable acoustic delay-line (PADL) module is a feasible and effective solution for improving PAT systems.
    • This technology addresses key limitations in PAT by reducing costs and increasing imaging speed.
    • The PADL module holds significant potential for advancing biomedical imaging applications using photoacoustic tomography.