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Updated: Sep 27, 2025

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
Published on: September 20, 2018
Meiotic commitment: More than a transcriptional switch
Abhimannyu Rimal1, Edward Winter1
1Department of Biochemistry and Molecular Biology, Thomas Jefferson University, 922 Bluemle Life Science Building, 233 South 10(th) Street, Philadelphia, PA 19107, USA.
Abstract:
Commitment to cellular differentiation programs can be controlled by self-activating transcription factors that trigger the expression of cell-type-specific genes. A new study shows that, although commitment to meiosis in yeast is controlled in this manner, additional signaling interactions promote the committed state.
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