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Updated: Sep 27, 2025

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
The frequency of atrial infarction in patients with supraventricular arrhythmias
A V Bocharov1, L V Popov2, M D Lagkuev3
1Kostroma Regional Clinical Hospital named after Korolev E.I.; Republican Clinical Hospital of the Ministry of Health of the Republic of North Ossetia-Alania.
Insights
Atrial infarction (AI) occurs in nearly 10% of patients with supraventricular arrhythmias and elevated troponin I. Diagnosis requires ECG, biomarkers, and coronary angiography showing reduced blood flow in atrial arteries.
Area of Science:
- Cardiology
- Internal Medicine
- Pathophysiology
Background:
- Supraventricular arrhythmias, such as atrial fibrillation, can present with elevated cardiac biomarkers.
- The diagnosis of atrial infarction (AI) is often overlooked in these patients.
- Understanding the incidence and diagnostic markers of AI is crucial for patient management.
Purpose of the Study:
- To evaluate the incidence of atrial infarction (AI) in patients with supraventricular arrhythmias.
- To identify diagnostic signs of acute ischemic atrial damage using selective coronary angiography (CA).
- To determine the localization of lesions in acute ischemic atrial damage.
Main Methods:
- Retrospective review of 287 case reports of patients with supraventricular arrhythmia and positive troponin I.
- Pharmacological arrest of arrhythmia and subsequent ECG, troponin I, echocardiography, and CA.
- Analysis of ECG changes, myocardial damage markers, and coronary blood flow velocity.
Main Results:
- Signs of AI were present in 27% of patients; confirmed AI in 9.5% and probable AI in 17.5%.
- Confirmed AI required ECG changes, positive troponin I, and reduced blood flow in the sinoatrial nodal artery.
- Coronary angiography revealed no obstructive coronary artery disease but showed reduced blood flow (TIMI II) in 9.5% of cases.
Conclusions:
- Atrial infarction should be considered in patients with supraventricular arrhythmias, characteristic symptoms, and elevated myocardial injury enzymes.
- Diagnostic criteria for AI include ECG changes, elevated troponin I, and evidence of reduced blood flow in atrial arteries.
- Further research is needed to elucidate the specific mechanisms and long-term implications of atrial infarction.
Abstract:
Aim To evaluate the incidence of atrial infarction (AI) based on a retrospective review of 287 case reports of patients with supraventricular arrhythmia and a positive qualitative test for troponin I after pharmacological arrest of arrhythmia; to determine the target localization of lesions and diagnostic signs, that appear in acute ischemic atrial damage, by selective coronary angiography (CA).Material and methods A retrospective review was performed of 287 case reports of patients admitted to cardiology departments for atrial fibrillation paroxysm with narrow QRS complexes on electrocardiogram (ECG) from 2018 through 2020. At the prehospital stage, verapamil had been administered intravenously with no effect. In the hospital, the sinus rhythm was successfully restored pharmacologically in all patients. Then ECG, repeated qualitative determination of troponin I, echocardiography, and CA were performed.Results 77 (27 %) patients of the study group had AI signs; 27 (9.5 %) of these patients had confirmed AI, and 50 (17.5 %) patients had probable AI. The existence of acute ischemic injury was considered absolutely confirmed in the presence of a combination of ECG changes, positive markers of myocardial damage, and reduced blood flow velocity in the left atrial branch of the sinoatrial nodal artery as shown by CA; in the presence of only ECG and biochemical criteria, acute AI was considered probable. According to selective CA, coronary injuries requiring an intervention were absent, and signs of the above-mentioned artery thrombosis were not visualized. However, the blood flow velocity was reduced to the TIMI II level in 9.5 % of cases; other atrial branches had an extremely small diameter.Conclusion Atrial infarction needs to be excluded for patients with supraventricular arrhythmias, a characteristic clinical picture, and increased levels of myocardial injury enzymes.
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