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Perceval S, sutureless aortic valve: cost-consequence analysis.

Ioannis Panagiotopoulos1, Nikolaos Kotsopoulos2, Georgios-Ioannis Verras3

  • 1Department of Cardiothoracic Surgery, General University, Hospital of Patras, Patras, Greece.

Kardiochirurgia I Torakochirurgia Polska = Polish Journal of Cardio-Thoracic Surgery
|April 13, 2022
PubMed
Summary

Sutureless aortic valve replacement with the Perceval S valve is safe and effective. Shorter procedure times lead to better clinical outcomes and reduced hospital costs.

Keywords:
Perceval Saortic valve replacementcost effectivenesssutureless aortic valve

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Area of Science:

  • Cardiovascular Surgery
  • Medical Devices
  • Health Economics

Background:

  • Sutureless aortic valve prostheses offer potential for reduced ischemic times during surgery.
  • The economic impact of shortened operative times with sutureless valves requires further investigation.

Purpose of the Study:

  • To evaluate the clinical and economic impact of the Perceval S sutureless, self-expanding biological valve.
  • To determine if reduced operative times translate to lower hospital costs.

Main Methods:

  • Retrospective analysis comparing 29 patients receiving Crown PRT valve and 35 patients receiving Perceval S valve.
  • Data collected included preoperative details, hospital outcomes, and healthcare resource consumption.
  • Statistical analysis used chi-squared and t-tests.

Main Results:

  • Significantly shorter aortic cross-clamp, cardiopulmonary bypass, and operation times in the Perceval S group (p < 0.001).
  • Fewer blood transfusions and shorter intensive care unit (ICU) stays were observed in the sutureless group (p = 0.03 and p = 0.01, respectively).
  • Reduced resource consumption noted in the sutureless group due to shorter procedural and ICU times.

Conclusions:

  • The Perceval S valve demonstrates clinical safety and effectiveness.
  • Shorter procedural times associated with sutureless valves correlate with improved clinical outcomes and decreased hospital expenditures.