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Related Concept Videos

Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

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Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
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Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

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Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
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An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
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Coronary Artery Disease III: Clinical Manifestations01:30

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Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
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Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

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Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
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The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
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Updated: Sep 27, 2025

Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices
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Microsurgical Creation of Giant Bifurcation Aneurysms in Rabbits for the Evaluation of Endovascular Devices

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Multiple symptomatic giant coronary aneurysms.

Damir Vukomanovic1, Samuel Unzek1, William Reichert1

  • 1The University of Arizona College of Medicine Phoenix Arizona USA.

Clinical Case Reports
|April 13, 2022
PubMed
Summary
This summary is machine-generated.

Kawasaki disease can cause rare giant coronary artery aneurysms in elderly patients. Coronary artery bypass grafting provided symptom relief for a patient with left coronary system aneurysms.

Keywords:
CABGangiographycoronary aneurysmkawasaki

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Area of Science:

  • Cardiology
  • Pediatric Rheumatology
  • Vascular Medicine

Background:

  • Kawasaki disease (KD) is a leading cause of acquired heart disease in children.
  • Coronary artery aneurysms (CAAs) are a known complication of KD, but giant CAAs are rare.
  • CAA in elderly patients is exceptionally uncommon, particularly involving the left coronary system.

Observation:

  • A rare case of multiple giant coronary artery aneurysms (GCAs) in an elderly patient is presented.
  • The aneurysms predominantly affected the left coronary artery system, a less common distribution.
  • The patient presented with ischemic symptoms attributed to the GCAs.

Findings:

  • Symptomatic GCAs in an elderly patient secondary to Kawasaki disease.
  • Surgical intervention via coronary artery bypass grafting (CABG) was performed.
  • Successful symptom relief was achieved post-CABG.

Implications:

  • Highlights the potential for late-onset complications of Kawasaki disease.
  • Suggests CABG as a viable treatment option for symptomatic GCAs in elderly patients.
  • Underscores the importance of long-term cardiovascular surveillance in KD survivors.