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Nails Involvement in Winiwarter-Buerger Disease
Michela V R Starace1, Aurora Alessandrini1, Antonella Tosti2
1Department of Specialized, Experimental and Diagnostic Medicine, Dermatology-IRCCS, Policlinico Sant'Orsola, Alma Mater Studiorum, University of Bologna, Bologna, Italy.
Buerger disease (thromboangiitis obliterans) can manifest with unusual nail lesions, including chronic paronychia and leukonychia, as initial symptoms. This highlights the importance of considering these nail changes in diagnosing this rare vascular condition.
Area of Science:
- Vascular Medicine
- Dermatology
- Rheumatology
Background:
- Buerger disease, or thromboangiitis obliterans, is a rare inflammatory vascular condition affecting small and medium-sized vessels.
- It typically impacts young male smokers, primarily causing lower limb ischemia.
Observation:
- This report details two patients where nail abnormalities were the first presenting sign of Buerger disease.
- Observed nail lesions included chronic paronychia and proximal leukonychia with onycholysis and nail bed erosion.
Findings:
- Nail involvement is an uncommon manifestation of Buerger disease.
- The study identified two distinct nail lesion presentations not previously documented in medical literature.
Implications:
- Recognizing these specific nail changes can aid in the early diagnosis of Buerger disease.
- This expands the clinical spectrum of Buerger disease, emphasizing the need for thorough dermatological examination in affected patients.
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