Flexible polymeric patch based nanotherapeutics against non-cancer therapy

Area of Science:

• Biomedical Engineering
• Materials Science
• Nanotechnology

Background:

• Flexible polymeric patches are versatile biomedical devices due to their biocompatibility, biodegradability, and drug delivery capabilities.
• These patches, including microneedles and hydrogels, can be enhanced by integrating nanomaterials for improved therapeutic outcomes.
• Nanomaterial integration offers potential for on-demand drug administration, increased efficacy, and reduced systemic toxicity.

Purpose of the Study:

• To review flexible polymeric patches integrated with nanomaterials for biomedical applications.
• To discuss the advantages of these composite materials in drug delivery.
• To systematically review their applications in non-cancerous diseases.

Main Methods:

• Literature review of flexible polymeric patches combined with nanomaterials.
• Categorization of patches based on morphology (microneedles, hydrogels, etc.).
• Analysis of applications in various non-cancerous disease therapies.

Main Results:

• Nanomaterial-embedded polymeric patches demonstrate significant potential in treating conditions like diabetes, wounds, and dermatological diseases.
• These systems show promise for bone regeneration, cardiac repair, hair regrowth, obesity management, and immune disease therapy.
• The review identifies key advantages including enhanced curative efficacy and lowered systemic toxicity.

Conclusions:

• Flexible polymeric patches with nanomaterials represent a promising platform for advanced drug delivery systems.
• Further research is needed to address limitations and challenges for successful clinical translation.
• Future perspectives focus on optimizing these devices for targeted and regulated therapeutic interventions.