Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Ganglion Formation After Steroid Injection for Stenosing Flexor Tenosynovitis.

JB & JS open access·2025
Same author

Effects of regional variations and occupation on hand osteoarthritis: Insights from the research on osteoarthritis/osteoporosis against disability study.

Modern rheumatology·2025
Same author

Acute tenosynovitis following an accidental injection of Bacille Calmette-Guérin (BCG) in a health care worker: A case report.

Infection prevention in practice·2024
Same author

Psychometric Properties of the Turkish Version of the JHand for the Patient-Oriented Outcome Measure for Patients with Hand and Elbow Disorders.

Evaluation & the health professions·2022
Same author

New body surface indexes for germinal matrix: DIP joint extension boundary line and dorsal distal interphalangeal crease.

Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association·2022
Same author

Risk factors for residual pain after ligament reconstruction and tendon interposition on osteoarthritis of the first carpometacarpal joint.

Journal of orthopaedic surgery (Hong Kong)·2022

Related Experiment Video

Updated: Sep 27, 2025

A Novel Tenorrhaphy Suture Technique with Tissue Engineered Collagen Graft to Repair Large Tendon Defects
06:36

A Novel Tenorrhaphy Suture Technique with Tissue Engineered Collagen Graft to Repair Large Tendon Defects

Published on: December 10, 2021

3.0K

Robust Suture Combination for Rat Flexor Tendon Repair Model.

Yasuhide Iwanaga1, Yutaka Morizaki1, Kosuke Uehara1

  • 1Department of Sensory and Motor System Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.

Journal of Hand Surgery Global Online
|April 13, 2022
PubMed
Summary

A novel suture technique combining figure-of-eight peripheral and 2-strand core sutures effectively repaired rat flexor tendons. This method prevented rerupture without immobilization, offering a viable model for clinical settings.

Keywords:
Flexor tendon repairRat modelUltimate strength

More Related Videos

Using Q Suture to Enhance Resistance to Gap Formation and Tensile Strength of Repaired Flexor Tendons
10:32

Using Q Suture to Enhance Resistance to Gap Formation and Tensile Strength of Repaired Flexor Tendons

Published on: June 3, 2020

5.8K
Adjustable Stiffness, External Fixator for the Rat Femur Osteotomy and Segmental Bone Defect Models
10:09

Adjustable Stiffness, External Fixator for the Rat Femur Osteotomy and Segmental Bone Defect Models

Published on: October 9, 2014

22.8K

Related Experiment Videos

Last Updated: Sep 27, 2025

A Novel Tenorrhaphy Suture Technique with Tissue Engineered Collagen Graft to Repair Large Tendon Defects
06:36

A Novel Tenorrhaphy Suture Technique with Tissue Engineered Collagen Graft to Repair Large Tendon Defects

Published on: December 10, 2021

3.0K
Using Q Suture to Enhance Resistance to Gap Formation and Tensile Strength of Repaired Flexor Tendons
10:32

Using Q Suture to Enhance Resistance to Gap Formation and Tensile Strength of Repaired Flexor Tendons

Published on: June 3, 2020

5.8K
Adjustable Stiffness, External Fixator for the Rat Femur Osteotomy and Segmental Bone Defect Models
10:09

Adjustable Stiffness, External Fixator for the Rat Femur Osteotomy and Segmental Bone Defect Models

Published on: October 9, 2014

22.8K

Area of Science:

  • Orthopedic Surgery
  • Biomedical Engineering
  • Regenerative Medicine

Background:

  • Flexor tendon injuries require robust repair methods.
  • Existing models may not fully replicate clinical scenarios.
  • Need for effective surgical techniques to ensure tendon healing and function.

Purpose of the Study:

  • To develop and validate a rat flexor tendon repair model.
  • To compare the efficacy of different suture combinations.
  • To establish a model applicable to clinical settings and translational research.

Main Methods:

  • Three groups of rat flexor tendons were repaired using distinct suture combinations: Group A (3 single peripheral + 2-strand core), Group B (3 figure-of-eight peripheral alone), and Group C (3 figure-of-eight peripheral + 2-strand core).
  • Repaired tendons underwent in vitro biomechanical testing for tensile strength.
  • In vivo assessments included rerupture rates within three weeks and histological analysis.

Main Results:

  • Group C demonstrated superior ultimate tensile strength in biomechanical tests.
  • No reruptures occurred in Group C tendons within three weeks post-surgery.
  • Groups A and B exhibited significant rerupture rates, with observed fibrous scar tissue at tendon stumps, unlike Group C.

Conclusions:

  • The combination of figure-of-eight peripheral sutures and a 2-strand core suture provides sufficient strength for flexor tendon repair in rats.
  • This technique enables successful repair without the need for cast fixation or post-operative immobilization.
  • The developed model effectively mimics clinical flexor tendon repair and supports in vivo translational studies.