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Updated: Sep 27, 2025
Toxicological Assays for Testing Effects of an Epigenetic Drug on Development, Fecundity and Survivorship of Malaria Mosquitoes
Published on: January 16, 2015
Long-lasting insecticide-treated net use and malaria infections on the Kenyan coast
Alice Kamau1, Moses Musau1, Grace Mtanje1
1KEMRI-Wellcome Trust Research Programme, P.O. Box 43640-00100, Nairobi, Kenya.
Background:
A study was conducted to examine the impact of long-lasting insecticide-treated net (LLIN) use on the prevalence of malaria infections across all ages, 25 y after a trial of insecticide-treated nets was conducted in the same area along the Kenyan coast.
Methods:
The study comprised four community-based infection surveys and a simultaneous 12-month surveillance at six government outpatient health facilities (March 2018-February 2019). Logistic regression was used to examine the effect of LLIN use on malaria infections across all ages.
Results:
There was a high level of reported LLIN use by the community (72%), notably among children <5 y of age (84%). Across all ages, the adjusted odds ratio of LLIN use against asymptomatic parasitaemia in community surveys was 0.45 (95% confidence interval [CI] 0.36 to 0.57; p<0.001) and against fevers associated with infection presenting to health facilities was 0.63 (95% CI 0.58 to 0.68; p<0.001).
Conclusions:
There was significant protection of LLIN use against malaria infections across all ages.
