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Related Concept Videos

Autism Spectrum Disorder01:19

Autism Spectrum Disorder

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Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
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Related Experiment Video

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Eye Tracking Young Children with Autism
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Identifying Visual Attention Features Accurately Discerning Between Autism and Typically Developing: a Deep Learning

Jin Xie1,2, Longfei Wang1, Paula Webster3

  • 1The Brain Cognition and Brain Disease Institute, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, 518055, China.

Interdisciplinary Sciences, Computational Life Sciences
|April 13, 2022
PubMed
Summary
This summary is machine-generated.

Researchers identified novel visual attention patterns in autism spectrum disorder (ASD) using deep learning. This framework accurately distinguishes individuals with ASD, revealing new attention features like food and outdoor objects.

Keywords:
Autism spectrum disorderDeep learningEye movementVisual attention

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Area of Science:

  • Neuroscience
  • Computer Science
  • Developmental Psychology

Background:

  • Atypical visual attention is a key characteristic of autism spectrum disorder (ASD).
  • Accurately identifying individual-level attention features to differentiate between ASD and typically developing (TD) individuals remains difficult.

Purpose of the Study:

  • To develop a systematic framework for identifying discriminative visual attention features in ASD.
  • To achieve high accuracy in classifying individuals with ASD using deep learning models.
  • To uncover novel attention features beyond previously known ones.

Main Methods:

  • Developed a novel deep learning framework combining classification, segmentation, and image ablation.
  • Utilized a two-stream model achieving state-of-the-art performance.
  • Employed a direct measurement of classification ability to identify key features.

Main Results:

  • The two-stream model achieved a classification accuracy of 0.95.
  • Identified 'Food & drink' and 'Outdoor-objects' as new discriminative attention features, alongside 'Center-object' and 'Human-faces'.
  • A combined set of top-9 features yielded an AUC of 0.92 for individual-level classification.
  • A small dataset (12 images) achieved an AUC of 0.86, indicating potential for efficient diagnosis.

Conclusions:

  • The deep learning framework based on VGG-16 effectively recognizes and interprets abnormal visual attention in ASD.
  • The identified features, including novel categories, enhance understanding of ASD-related behaviors.
  • This approach offers a powerful tool for identifying biomarkers and facilitating clinical diagnosis of ASD.