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Updated: Sep 27, 2025

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Erasmus syndrome: The association of systemic sclerosis and silicosis
Miguel Osejo-Betancourt1, Pedro Chaparro-Mutiz2
1Pneumology, Hospital Santa Clara, Bogotá. mosejob@unbosque.edu.co.
Abstract:
Erasmus syndrome is the association of the exposure to silica and the subsequent development of systemic sclerosis, a rare occurrence, with scarce data in medical literature, which can be attributed to little knowledge of the syndrome and underdiagnosis. It is important to recognize this association as it has a worse respiratory prognosis than the idiopathic form of systemic sclerosis and since autoimmune diseases are rarer in men, it is easy to do exposure research when they occur. We describe the case of a 59-year-old man, a bricklayer by craft since the age of 15, who presented with respiratory symptoms and skin alterations and in whom this syndrome was diagnosed during his recent admission.
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