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Updated: Sep 27, 2025

An Assay for Measuring the Effects of Ethanol on the Locomotion Speed of Caenorhabditis elegans
Published on: April 9, 2015
[About the effect of ethanol on the level of substances of low and medium molecular weight]
I S Edelev1, N A Andriyanova1, L M Obukhova2
1Nizhny Novgorod regional Bureau of forensic medical examination, Nizhny Novgorod, Russia.
Abstract:
The aim of this work is to study the effect of the concentration of ethanol in the blood on the level of low and medium molecular weight substances in the urine and blood of corpses. The content of LMMWS in the blood and urine of corpses without ethanol in the blood and its concentration of 0.5-1.5 ‰ and 2.0-5.0 ‰ was determined by the method of Malakhova modified by Kopytova at wavelengths of 238-298 nm. The dependence of the concentration of LMMWS in urine on the concentration of ethanol in the blood is shown: the decrease in the parameters of LMMWS in urine is the more pronounced, the higher the concentration of ethanol in the blood. One of the probable mechanisms of such a decrease is the neurotoxic effect of ethanol, leading to polyuria and a decrease in the concentration of various substances in the urine.
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