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[Determination of zaleplon and clobazam by high performance liquid chromatography - high resolution tandem mass
R A Kalyokin1, N E Moskaleva1,2, A A Volkova1
1Russian Center of Forensic Medical Expertise, Moscow, Russia.
The Aim Of The Study:
Was to develop a method for the qualitative and quantitative determination of benzodiazepine receptor agonists (zaleplon and clobazam), taking into account different chemical structures, by high-performance liquid chromatography-high-resolution tandem mass spectrometry using Orbitrap technology for the purposes and tasks of forensic medical examination. A method has been developed for the identification and quantitative determination of zaleplon and clobazam by high-performance liquid chromatography-high-resolution tandem mass spectrometry using Orbitrap technology. The proposed identification method can be used in the future to form a database of domestic mass spectra for potent and narcotic substances.
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