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Pediatric gastrointestinal neuromodulation: A review
Khalil I El-Chammas1, Neha R Santucci1, Sherief Mansi1
1Cincinnati Children's Hospital Medical Center; Department of Pediatrics, University of Cincinnati, College of Medicine, Cincinnati, Ohio, USA.
Summary
Neuromodulation, using electrical nerve stimulation, offers new treatments for pediatric gastrointestinal issues like gastroparesis, constipation, and pain. This approach shows promise for improving motility and functional disorders in children.
Area of Science:
- Gastroenterology
- Neurology
- Pediatrics
Background:
- Neuromodulation, or neurostimulation, involves therapeutic electrical stimulation of nerves or brain centers.
- It is increasingly applied to various human diseases, including gastrointestinal disorders.
- Pediatric motility and functional disorders represent a recent and developing area for neuromodulation research.
Purpose of the Study:
- To review the application of neuromodulation in treating pediatric gastrointestinal disorders.
- To discuss its potential for managing pediatric gastroparesis, constipation, and visceral hyperalgesia.
Main Methods:
- This is a review article.
- It synthesizes current understanding and research on neuromodulation for pediatric GI conditions.
Main Results:
- Neuromodulation is an emerging therapeutic option for pediatric gastrointestinal motility and functional disorders.
- Specific conditions like gastroparesis, constipation, and visceral hyperalgesia are being explored.
Conclusions:
- Neuromodulation presents a promising frontier for treating complex pediatric gastrointestinal conditions.
- Further research and clinical trials are likely to expand its role in pediatric gastroenterology.
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