Related Experiment Video
Updated: Sep 27, 2025

05:02
Using Unidirectional Rotations to Improve Vestibular System Asymmetry in Patients with Vestibular Dysfunction
Published on: August 30, 2019
7.4K
Vitamin D Insufficiency/Deficiency in Patients with Recurrent Benign Paroxysmal Positional Vertigo
Rudi Pecci1, Marco Mandalà2, Antonella Marcari1
1Department of Oncology and Robotic Surgery, Unit of Audiology, Oncological and Robotic Head and Neck Surgery, Florence, Italy.
The Journal of International Advanced Otology
|April 14, 2022
Summary
Vitamin D deficiency is linked to benign paroxysmal positional vertigo (BPPV). Correcting this deficiency reduces BPPV relapses and the number of patients experiencing them.
Area of Science:
- Neurology
- Endocrinology
Background:
- Hypovitaminosis D, or vitamin D deficiency, is a growing concern.
- Benign paroxysmal positional vertigo (BPPV) is a common vestibular disorder.
Purpose of the Study:
- To investigate the association between vitamin D levels and BPPV.
- To determine if vitamin D supplementation impacts BPPV relapse rates.
- To assess if correcting vitamin D deficiency improves BPPV treatment outcomes.
Main Methods:
- A cohort of 26 BPPV patients and 24 controls were analyzed.
- Serum 25(OH) vitamin D levels were measured in all participants.
- BPPV patients received physical therapy and, if deficient, vitamin D (cholecalciferol) supplementation.
Main Results:
- A significant relationship was found between vitamin D deficiency and BPPV onset.
- Correction of hypovitaminosis D led to a reduction in BPPV relapses.
- Fewer patients experienced recurrent BPPV after vitamin D supplementation.
Conclusions:
- Vitamin D deficiency is associated with the occurrence of BPPV.
- Supplementation helps reduce BPPV recurrence.
- Vitamin D supplementation did not significantly alter BPPV response to physical therapy.
Related Concept Videos
Equilibrium and Balance
5.1K
The inner ear assumes dual functionalities of auditory perception and equilibrium maintenance. The vestibule is the organ responsible for balance. This organ contains mechanoreceptors, specifically hair cells, endowed with stereocilia, which aid in deciphering information regarding the position and motion of our heads. Two intrinsic components, the utricle and saccule, help perceive head position, while the semicircular canals track head movement. Neurological messages initiated in the...
5.1K
The Vestibular System
40.3K
The vestibular system is a set of inner ear structures that provide a sense of balance and spatial orientation. This system is comprised of structures within the labyrinth of the inner ear, including the cochlea and two otolith organs—the utricle and saccule. The labyrinth also contains three semicircular canals—superior, posterior, and horizontal—that are oriented on different planes.
40.3K
Bone Disorders
4.1K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
4.1K
Vitamins
1.0K
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
1.0K
Role of Vitamins in Maintaining Bone Health
3.8K
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
3.8K
Alterations in Blood Pressure
1.5K
Alterations in blood pressure, such as hypertension (high blood pressure) and hypotension (low blood pressure), significantly affect human health. Understanding these conditions' classifications, causes, and symptoms is essential for effective management and treatment.
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
1.5K

